Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
MA_10434231g0010.g
View in Genome Browser
Position
MA_10434231:26606-28839 (-)
2233bp
Gene Type
gene
Gene Description (Protein Product)
Belongs to the MCM family
Organism
Picea abies
Also AS AT2G16440

Gene Structure

upstream:
Get Sequence

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
MA_138102g0010.g Belongs to the MCM family
MA_163650g0010.g Belongs to the MCM family
MA_927111g0010.g Belongs to the MCM family
Regulatory gene
MA_10048467g0010.g SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MA_10157944g0010.g transcription
MA_101790g0010.g transcription

Load All Networks

Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000228 nuclear chromosome CC
GO:0000278 mitotic cell cycle BP
GO:0000724 double-strand break repair via homologous recombination BP
GO:0000725 recombinational repair BP
GO:0000727 double-strand break repair via break-induced replication BP
GO:0000785 chromatin CC
GO:0000790 chromatin CC
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003682 chromatin binding MF
GO:0003688 DNA replication origin binding MF
GO:0003690 double-stranded DNA binding MF
GO:0003697 single-stranded DNA binding MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005656 nuclear pre-replicative complex CC
GO:0005657 replication fork CC
GO:0005694 chromosome CC
GO:0005730 nucleolus CC
GO:0005737 cytoplasm CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006260 DNA replication BP
GO:0006261 DNA-templated DNA replication BP
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication BP
GO:0006268 DNA unwinding involved in DNA replication BP
GO:0006270 DNA replication initiation BP
GO:0006271 DNA strand elongation involved in DNA replication BP
GO:0006275 regulation of DNA replication BP
GO:0006279 premeiotic DNA replication BP
GO:0006281 DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006310 DNA recombination BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008156 negative regulation of DNA replication BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009889 regulation of biosynthetic process BP
GO:0009890 negative regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010558 negative regulation of macromolecule biosynthetic process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010639 negative regulation of organelle organization BP
GO:0016043 cellular component organization BP
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0022607 cellular component assembly BP
GO:0022616 DNA strand elongation BP
GO:0030174 regulation of DNA-templated DNA replication initiation BP
GO:0030874 nucleolar chromatin CC
GO:0030875 rDNA protrusion CC
GO:0031261 DNA replication preinitiation complex CC
GO:0031298 replication fork protection complex CC
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031327 negative regulation of cellular biosynthetic process BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032392 DNA geometric change BP
GO:0032508 DNA duplex unwinding BP
GO:0032780 negative regulation of ATP-dependent activity BP
GO:0032991 protein-containing complex CC
GO:0032993 protein-DNA complex CC
GO:0033043 regulation of organelle organization BP
GO:0033044 regulation of chromosome organization BP
GO:0033260 nuclear DNA replication BP
GO:0033554 cellular response to stress BP
GO:0034622 protein-containing complex assembly BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0036387 pre-replicative complex CC
GO:0036388 pre-replicative complex assembly BP
GO:0042555 MCM complex CC
GO:0043086 negative regulation of catalytic activity BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043462 regulation of ATP-dependent activity BP
GO:0043565 sequence-specific DNA binding MF
GO:0043596 nuclear replication fork CC
GO:0043933 protein-containing complex organization BP
GO:0044085 cellular component biogenesis BP
GO:0044092 negative regulation of molecular function BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044427 obsolete chromosomal part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044451 obsolete nucleoplasm part CC
GO:0044452 obsolete nucleolar part CC
GO:0044454 obsolete nuclear chromosome part CC
GO:0044464 obsolete cell part CC
GO:0044786 cell cycle DNA replication BP
GO:0045005 DNA-templated DNA replication maintenance of fidelity BP
GO:0045934 negative regulation of nucleobase-containing compound metabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0048478 replication fork protection BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050790 regulation of catalytic activity BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051052 regulation of DNA metabolic process BP
GO:0051053 negative regulation of DNA metabolic process BP
GO:0051095 regulation of helicase activity BP
GO:0051097 negative regulation of helicase activity BP
GO:0051128 regulation of cellular component organization BP
GO:0051129 negative regulation of cellular component organization BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051276 chromosome organization BP
GO:0051321 meiotic cell cycle BP
GO:0051336 regulation of hydrolase activity BP
GO:0051346 negative regulation of hydrolase activity BP
GO:0051716 cellular response to stimulus BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065003 protein-containing complex assembly BP
GO:0065004 protein-DNA complex assembly BP
GO:0065007 biological regulation BP
GO:0065009 regulation of molecular function BP
GO:0070013 intracellular organelle lumen CC
GO:0071103 DNA conformation change BP
GO:0071162 CMG complex CC
GO:0071704 organic substance metabolic process BP
GO:0071824 protein-DNA complex subunit organization BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080090 regulation of primary metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090329 regulation of DNA-templated DNA replication BP
GO:0097159 organic cyclic compound binding MF
GO:0097373 MCM core complex CC
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901576 organic substance biosynthetic process BP
GO:1902292 cell cycle DNA replication initiation BP
GO:1902299 pre-replicative complex assembly involved in cell cycle DNA replication BP
GO:1902315 nuclear cell cycle DNA replication initiation BP
GO:1902449 regulation of DNA helicase activity BP
GO:1902450 negative regulation of DNA helicase activity BP
GO:1902969 mitotic DNA replication BP
GO:1902975 mitotic DNA replication initiation BP
GO:1903046 meiotic cell cycle process BP
GO:1903047 mitotic cell cycle process BP
GO:1905462 regulation of DNA duplex unwinding BP
GO:1905463 negative regulation of DNA duplex unwinding BP
GO:1905774 regulation of DNA helicase activity BP
GO:1905775 negative regulation of DNA helicase activity BP
GO:1990837 sequence-specific double-stranded DNA binding MF
GO:2000104 negative regulation of DNA-templated DNA replication BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000113 negative regulation of cellular macromolecule biosynthetic process BP
GO:2001251 negative regulation of chromosome organization BP
KEGG Term Name Description
map03030 DNA replication A complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM complex) precedes the DNA synthetic machinery and unwinds the duplex parental DNA in cooperation with the SSB or RPA. On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication occurs discontinuously by synthesis and joining of short Okazaki fragments. In prokaryotes, the leading strand replication apparatus consists of a DNA polymerase (pol III core), a sliding clamp (beta), and a clamp loader (gamma delta complex). The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA primer is removed either by an RNase H or by the 5 to 3 exonuclease activity of DNA pol I, and the DNA ligase joins the Okazaki fragments. In eukaryotes, three DNA polymerases (alpha, delta, and epsilon) have been identified. DNA primase forms a permanent complex with DNA polymerase alpha. PCNA and RFC function as a clamp and a clamp loader. FEN 1 and RNase H1 remove the RNA from the Okazaki fragments and DNA ligase I joins the DNA.