Basic Information
Gene ID
Position
scaffold_510:4205419-4277267 (-)
71848bp
Gene Type
gene
Gene Description (Protein Product)
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Organism
Also AS AT1G59900

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
PILA_36285.g of pyruvate dehydrogenase complex
PILA_36891.g Pyruvate kinase
PILA_35539.g Dihydrolipoyl dehydrogenase
Regulatory gene
PILA_00148.g homeobox-leucine zipper protein
PILA_00290.g MADS-box transcription factor
PILA_00306.g transcription factor

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0005759 mitochondrial matrix CC
GO:0005829 cytosol CC
GO:0006950 response to stress BP
GO:0006970 response to osmotic stress BP
GO:0008150 biological_process BP
GO:0008270 zinc ion binding MF
GO:0009628 response to abiotic stimulus BP
GO:0009651 response to salt stress BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0031974 membrane-enclosed lumen CC
GO:0042221 response to chemical BP
GO:0043167 ion binding MF
GO:0043169 cation binding MF
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044429 obsolete mitochondrial part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046686 response to cadmium ion BP
GO:0046872 metal ion binding MF
GO:0046914 transition metal ion binding MF
GO:0050896 response to stimulus BP
GO:0050897 cobalt ion binding MF
GO:0070013 intracellular organelle lumen CC
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00620 Pyruvate metabolism -
map00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].
map00010 Glycolysis / Gluconeogenesis Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which often corresponds to operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].