Basic Information
Gene Structure
Domain
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
PILA_27737.g
View in Genome Browser
Position
scaffold_9901:239365-244609 (-)
5244bp
Gene Type
gene
Gene Description (Protein Product)
Binds the poly(A) tail of mRNA
Organism
Pinus lambertiana
Also AS AT2G23350

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description


Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003723 RNA binding MF
GO:0003729 mRNA binding MF
GO:0003743 translation initiation factor activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0006412 translation BP
GO:0006413 translational initiation BP
GO:0006417 regulation of translation BP
GO:0006446 regulation of translational initiation BP
GO:0006518 peptide metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006970 response to osmotic stress BP
GO:0008135 translation factor activity, RNA binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009628 response to abiotic stimulus BP
GO:0009651 response to salt stress BP
GO:0009889 regulation of biosynthetic process BP
GO:0009894 regulation of catabolic process BP
GO:0009987 cellular process BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0010467 gene expression BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010608 post-transcriptional regulation of gene expression BP
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031329 regulation of cellular catabolic process BP
GO:0032268 regulation of protein metabolic process BP
GO:0034248 regulation of amide metabolic process BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0042221 response to chemical BP
GO:0043043 peptide biosynthetic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043603 amide metabolic process BP
GO:0043604 amide biosynthetic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044271 cellular nitrogen compound biosynthetic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044464 obsolete cell part CC
GO:0046686 response to cadmium ion BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0061013 regulation of mRNA catabolic process BP
GO:0065007 biological regulation BP
GO:0071704 organic substance metabolic process BP
GO:0080090 regulation of primary metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay BP
GO:1901363 heterocyclic compound binding MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901566 organonitrogen compound biosynthetic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1903311 regulation of mRNA metabolic process BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
KEGG Term Name Description
map03018 RNA degradation The correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay exist and both pathways are initiated by poly(A) shortening of the mRNA. In the 5' to 3' pathway, this is followed by decapping which then permits the 5' to 3' exonucleolytic degradation of transcripts. In the 3' to 5' pathway, the exosome, a large multisubunit complex, plays a key role. The exosome exists in archaeal cells, too. In bacteria, endoribonuclease E, a key enzyme involved in RNA decay and processing, organizes a protein complex called degradosome. RNase E or R interacts with the phosphate-dependent exoribonuclease polynucleotide phosphorylase, DEAD-box helicases, and additional factors in the RNA-degrading complex.
map03015 mRNA surveillance pathway The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins.