Basic Information
Gene ID
Position
chr1:1244892279-1244900042 (+)
7763bp
Gene Type
gene
Gene Description (Protein Product)
Belongs to the isocitrate and isopropylmalate dehydrogenases family
Organism
Also AS AT1G65930

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Pt4G08000 Alanine aminotransferase
Pt1G72570 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Pt7G60620 Carbon-nitrogen hydrolase
Regulatory gene
Pt0G00840 WRKY Transcription Factor
Pt0G20740 (No apical meristem) protein
Pt0G30790 Myb family transcription factor

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004448 isocitrate dehydrogenase [NAD(P)+] activity MF
GO:0004450 isocitrate dehydrogenase (NADP+) activity MF
GO:0005488 binding MF
GO:0005507 copper ion binding MF
GO:0005575 cellular_component CC
GO:0005576 extracellular region CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0005886 plasma membrane CC
GO:0005911 cell-cell junction CC
GO:0006082 organic acid metabolic process BP
GO:0006102 isocitrate metabolic process BP
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006732 obsolete coenzyme metabolic process BP
GO:0006733 obsolete oxidoreduction coenzyme metabolic process BP
GO:0006739 NADP metabolic process BP
GO:0006753 nucleoside phosphate metabolic process BP
GO:0006793 phosphorus metabolic process BP
GO:0006796 phosphate-containing compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006952 defense response BP
GO:0006970 response to osmotic stress BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009117 nucleotide metabolic process BP
GO:0009506 plasmodesma CC
GO:0009507 chloroplast CC
GO:0009532 plastid stroma CC
GO:0009536 plastid CC
GO:0009570 chloroplast stroma CC
GO:0009605 response to external stimulus BP
GO:0009607 response to biotic stimulus BP
GO:0009617 response to bacterium BP
GO:0009628 response to abiotic stimulus BP
GO:0009651 response to salt stress BP
GO:0009987 cellular process BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0010043 response to zinc ion BP
GO:0016020 membrane CC
GO:0016491 oxidoreductase activity MF
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors MF
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor MF
GO:0019362 pyridine nucleotide metabolic process BP
GO:0019637 organophosphate metabolic process BP
GO:0019752 carboxylic acid metabolic process BP
GO:0030054 cell junction CC
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0042221 response to chemical BP
GO:0042742 defense response to bacterium BP
GO:0043167 ion binding MF
GO:0043169 cation binding MF
GO:0043207 response to external biotic stimulus BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043436 oxoacid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044281 small molecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044434 obsolete chloroplast part CC
GO:0044435 obsolete plastid part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0046496 nicotinamide nucleotide metabolic process BP
GO:0046686 response to cadmium ion BP
GO:0046872 metal ion binding MF
GO:0046914 transition metal ion binding MF
GO:0048046 apoplast CC
GO:0050896 response to stimulus BP
GO:0051186 obsolete cofactor metabolic process BP
GO:0051704 obsolete multi-organism process BP
GO:0051707 response to other organism BP
GO:0055044 symplast CC
GO:0055086 nucleobase-containing small molecule metabolic process BP
GO:0055114 obsolete oxidation-reduction process BP
GO:0071704 organic substance metabolic process BP
GO:0071944 cell periphery CC
GO:0072350 tricarboxylic acid metabolic process BP
GO:0072524 pyridine-containing compound metabolic process BP
GO:0098542 defense response to other organism BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1901564 organonitrogen compound metabolic process BP
KEGG Term Name Description
map04146 Peroxisome Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00480 Glutathione metabolism -
map00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].