Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000166 | nucleotide binding | MF |
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004448 | isocitrate dehydrogenase [NAD(P)+] activity | MF |
| GO:0004449 | isocitrate dehydrogenase (NAD+) activity | MF |
| GO:0005488 | binding | MF |
| GO:0005524 | ATP binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005739 | mitochondrion | CC |
| GO:0006082 | organic acid metabolic process | BP |
| GO:0006091 | generation of precursor metabolites and energy | BP |
| GO:0006099 | tricarboxylic acid cycle | BP |
| GO:0006101 | citrate metabolic process | BP |
| GO:0006102 | isocitrate metabolic process | BP |
| GO:0008144 | obsolete drug binding | MF |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0008270 | zinc ion binding | MF |
| GO:0009060 | aerobic respiration | BP |
| GO:0009507 | chloroplast | CC |
| GO:0009536 | plastid | CC |
| GO:0009987 | cellular process | BP |
| GO:0015980 | energy derivation by oxidation of organic compounds | BP |
| GO:0016491 | oxidoreductase activity | MF |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | MF |
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | MF |
| GO:0016999 | antibiotic metabolic process | BP |
| GO:0017076 | purine nucleotide binding | MF |
| GO:0017144 | xenobiotic metabolic process | BP |
| GO:0019752 | carboxylic acid metabolic process | BP |
| GO:0030554 | adenyl nucleotide binding | MF |
| GO:0032553 | ribonucleotide binding | MF |
| GO:0032555 | purine ribonucleotide binding | MF |
| GO:0032559 | adenyl ribonucleotide binding | MF |
| GO:0035639 | purine ribonucleoside triphosphate binding | MF |
| GO:0036094 | small molecule binding | MF |
| GO:0043167 | ion binding | MF |
| GO:0043168 | anion binding | MF |
| GO:0043169 | cation binding | MF |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043436 | oxoacid metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044281 | small molecule metabolic process | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0045333 | cellular respiration | BP |
| GO:0046872 | metal ion binding | MF |
| GO:0046914 | transition metal ion binding | MF |
| GO:0055114 | obsolete oxidation-reduction process | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0072350 | tricarboxylic acid metabolic process | BP |
| GO:0097159 | organic cyclic compound binding | MF |
| GO:0097367 | carbohydrate derivative binding | MF |
| GO:1901265 | nucleoside phosphate binding | MF |
| GO:1901363 | heterocyclic compound binding | MF |
| KEGG Term | Name | Description |
|---|---|---|
| map01110 | Biosynthesis of secondary metabolites | - |
| map01100 | Metabolic pathways | - |
| map00020 | Citrate cycle (TCA cycle) | The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011]. |