Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0003909 | DNA ligase activity | MF |
| GO:0003910 | DNA ligase (ATP) activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0006259 | DNA metabolic process | BP |
| GO:0006260 | DNA replication | BP |
| GO:0006261 | DNA-templated DNA replication | BP |
| GO:0006266 | DNA ligation | BP |
| GO:0006271 | DNA strand elongation involved in DNA replication | BP |
| GO:0006273 | lagging strand elongation | BP |
| GO:0006281 | DNA repair | BP |
| GO:0006725 | cellular aromatic compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0006950 | response to stress | BP |
| GO:0006974 | cellular response to DNA damage stimulus | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009058 | biosynthetic process | BP |
| GO:0009059 | macromolecule biosynthetic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0016070 | RNA metabolic process | BP |
| GO:0016874 | ligase activity | MF |
| GO:0016886 | ligase activity, forming phosphoric ester bonds | MF |
| GO:0022616 | DNA strand elongation | BP |
| GO:0033554 | cellular response to stress | BP |
| GO:0034641 | cellular nitrogen compound metabolic process | BP |
| GO:0034645 | cellular macromolecule biosynthetic process | BP |
| GO:0043170 | macromolecule metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044249 | cellular biosynthetic process | BP |
| GO:0044260 | cellular macromolecule metabolic process | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0046483 | heterocycle metabolic process | BP |
| GO:0050896 | response to stimulus | BP |
| GO:0051103 | DNA ligation involved in DNA repair | BP |
| GO:0051716 | cellular response to stimulus | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0090304 | nucleic acid metabolic process | BP |
| GO:0140097 | catalytic activity, acting on DNA | MF |
| GO:1901360 | organic cyclic compound metabolic process | BP |
| GO:1901576 | organic substance biosynthetic process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map03410 | Base excision repair | Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates. |