PPGR - Gene Detail

Basic Information

Gene ID	gene-LOC118053285 View in Genome Browser
Position	NW_023271518.1:737883-740991 (+) 3108bp
Gene Type	gene
Gene Description (Protein Product)	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Organism	Populus alba
Also AS	Potri.013G031100AT1G08830Potri.013G031100.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-LOC118056750 Destroys radicals which are normally produced within the cells and which are toxic to biological systems

gene-LOC118059530 Ubiquitin family

gene-LOC118062990 Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked

Regulatory gene

gene-LOC118027806 Cyclic dof factor

gene-LOC118028055 Dof zinc finger protein

gene-LOC118028114 dof zinc finger protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000302	response to reactive oxygen species	BP
GO:0000303	response to superoxide	BP
GO:0000305	response to oxygen radical	BP
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004784	superoxide dismutase activity	MF
GO:0005488	binding	MF
GO:0005507	copper ion binding	MF
GO:0005575	cellular_component	CC
GO:0005576	extracellular region	CC
GO:0005615	extracellular space	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0006801	superoxide metabolic process	BP
GO:0006950	response to stress	BP
GO:0006979	response to oxidative stress	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008270	zinc ion binding	MF
GO:0009636	response to toxic substance	BP
GO:0009987	cellular process	BP
GO:0010035	response to inorganic substance	BP
GO:0016209	antioxidant activity	MF
GO:0016491	oxidoreductase activity	MF
GO:0016721	oxidoreductase activity, acting on superoxide radicals as acceptor	MF
GO:0019430	removal of superoxide radicals	BP
GO:0033554	cellular response to stress	BP
GO:0034599	cellular response to oxidative stress	BP
GO:0034614	cellular response to reactive oxygen species	BP
GO:0042221	response to chemical	BP
GO:0043167	ion binding	MF
GO:0043169	cation binding	MF
GO:0044237	cellular metabolic process	BP
GO:0044421	obsolete extracellular region part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044464	obsolete cell part	CC
GO:0046872	metal ion binding	MF
GO:0046914	transition metal ion binding	MF
GO:0050896	response to stimulus	BP
GO:0051716	cellular response to stimulus	BP
GO:0055114	obsolete oxidation-reduction process	BP
GO:0070887	cellular response to chemical stimulus	BP
GO:0071450	cellular response to oxygen radical	BP
GO:0071451	cellular response to superoxide	BP
GO:0072593	reactive oxygen species metabolic process	BP
GO:0097237	cellular response to toxic substance	BP
GO:0098754	detoxification	BP
GO:0098869	cellular oxidant detoxification	BP
GO:1901700	response to oxygen-containing compound	BP
GO:1901701	cellular response to oxygen-containing compound	BP
GO:1990748	cellular detoxification	BP

KEGG Term	Name	Description
map04146	Peroxisome	Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.