PPGR - Gene Detail

Gene ID	gene-LOC118061045 View in Genome Browser
Position	NW_023271747.1:402074-407929 (-) 5855bp
Gene Type	gene
Gene Description (Protein Product)	NEDD8-activating enzyme E1 catalytic
Organism	Populus alba
Also AS	Potri.008G204000AT5G19180Potri.008G204000.v4.1

upstream:

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Protein-protein interaction (PPI)	gene-LOC118063251 Belongs to the ubiquitin-conjugating enzyme family gene-LOC118062842 Belongs to the ubiquitin-conjugating enzyme family gene-LOC118062466 Belongs to the ubiquitin-conjugating enzyme family
Regulatory gene	gene-LOC118027806 Cyclic dof factor gene-LOC118028055 Dof zinc finger protein gene-LOC118028114 dof zinc finger protein

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Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0006464	protein modification process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008641	ubiquitin-like modifier activating enzyme activity	MF
GO:0009987	cellular process	BP
GO:0016874	ligase activity	MF
GO:0016877	ligase activity, forming carbon-sulfur bonds	MF
GO:0019538	protein metabolic process	BP
GO:0019781	NEDD8 activating enzyme activity	MF
GO:0032446	protein modification by small protein conjugation	BP
GO:0036211	protein modification process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043412	macromolecule modification	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044464	obsolete cell part	CC
GO:0045116	protein neddylation	BP
GO:0046982	protein heterodimerization activity	MF
GO:0046983	protein dimerization activity	MF
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0071704	organic substance metabolic process	BP
GO:1901564	organonitrogen compound metabolic process	BP

KEGG Term	Name	Description
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.