PPGR - Gene Detail

Basic Information

Gene ID	gene-LOC105138686 View in Genome Browser
Position	NW_011499961.1:142808-146933 (-) 4125bp
Gene Type	gene
Gene Description (Protein Product)	Belongs to the SKP1 family
Organism	Populus euphratica
Also AS	Potri.005G109900AT1G75950Potri.005G109900.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-LOC105139672 Belongs to the cullin family

gene-LOC105141229 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH

gene-LOC105140970 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH

Regulatory gene

gene-LOC105107546 Dof zinc finger protein

gene-LOC105107883 Dof zinc finger protein

gene-LOC105108074 Dof zinc finger protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0003006	developmental process involved in reproduction	BP
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0007275	multicellular organism development	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009790	embryo development	BP
GO:0009791	post-embryonic development	BP
GO:0009793	embryo development ending in seed dormancy	BP
GO:0009987	cellular process	BP
GO:0010154	fruit development	BP
GO:0019538	protein metabolic process	BP
GO:0019941	modification-dependent protein catabolic process	BP
GO:0022414	reproductive process	BP
GO:0030163	protein catabolic process	BP
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0048316	seed development	BP
GO:0048608	reproductive structure development	BP
GO:0048731	system development	BP
GO:0048856	anatomical structure development	BP
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0061458	reproductive system development	BP
GO:0071704	organic substance metabolic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901575	organic substance catabolic process	BP

KEGG Term	Name	Description
map04141	Protein processing in endoplasmic reticulum	The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.