PPGR - Gene Detail

Basic Information

Gene ID	gene-LOC105139413 View in Genome Browser
Position	NW_011499845.1:1641447-1644487 (+) 3040bp
Gene Type	gene
Gene Description (Protein Product)	Clathrin is the major protein of the polyhedral coat of coated pits and vesicles
Organism	Populus euphratica
Also AS	Potri.008G066800AT2G40060Potri.008G066800.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-LOC105139527 Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome

gene-LOC105142788 Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

gene-LOC105140227

Regulatory gene

gene-LOC105107546 Dof zinc finger protein

gene-LOC105107624 AP2-like ethylene-responsive transcription factor

gene-LOC105107883 Dof zinc finger protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0005198	structural molecule activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005886	plasma membrane	CC
GO:0006810	transport	BP
GO:0006897	endocytosis	BP
GO:0006898	receptor-mediated endocytosis	BP
GO:0008150	biological_process	BP
GO:0009504	cell plate	CC
GO:0009507	chloroplast	CC
GO:0009524	phragmoplast	CC
GO:0009526	plastid envelope	CC
GO:0009536	plastid	CC
GO:0009941	chloroplast envelope	CC
GO:0012506	vesicle membrane	CC
GO:0016020	membrane	CC
GO:0016192	vesicle-mediated transport	BP
GO:0030117	membrane coat	CC
GO:0030118	clathrin coat	CC
GO:0030120	vesicle coat	CC
GO:0030125	clathrin vesicle coat	CC
GO:0030135	coated vesicle	CC
GO:0030136	clathrin-coated vesicle	CC
GO:0030276	clathrin binding	MF
GO:0030659	cytoplasmic vesicle membrane	CC
GO:0030662	coated vesicle membrane	CC
GO:0030665	clathrin-coated vesicle membrane	CC
GO:0031090	organelle membrane	CC
GO:0031410	cytoplasmic vesicle	CC
GO:0031967	organelle envelope	CC
GO:0031975	envelope	CC
GO:0031982	vesicle	CC
GO:0032050	clathrin heavy chain binding	MF
GO:0032991	protein-containing complex	CC
GO:0042802	identical protein binding	MF
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044425	obsolete membrane part	CC
GO:0044433	obsolete cytoplasmic vesicle part	CC
GO:0044434	obsolete chloroplast part	CC
GO:0044435	obsolete plastid part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0048475	coated membrane	CC
GO:0051179	localization	BP
GO:0051234	establishment of localization	BP
GO:0071944	cell periphery	CC
GO:0072583	clathrin-dependent endocytosis	BP
GO:0097708	intracellular vesicle	CC
GO:0098588	bounding membrane of organelle	CC
GO:0098657	import into cell	BP
GO:0098796	membrane protein complex	CC
GO:0098805	membrane	CC

KEGG Term	Name	Description
map04144	Endocytosis	Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.