Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000060 | obsolete protein import into nucleus, translocation | BP |
| GO:0003674 | molecular_function | MF |
| GO:0005048 | signal sequence binding | MF |
| GO:0005215 | transporter activity | MF |
| GO:0005488 | binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005634 | nucleus | CC |
| GO:0005635 | nuclear envelope | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0006606 | protein import into nucleus | BP |
| GO:0006607 | NLS-bearing protein import into nucleus | BP |
| GO:0006610 | ribosomal protein import into nucleus | BP |
| GO:0006810 | transport | BP |
| GO:0006886 | intracellular protein transport | BP |
| GO:0006913 | nucleocytoplasmic transport | BP |
| GO:0008104 | protein localization | BP |
| GO:0008139 | nuclear localization sequence binding | MF |
| GO:0008150 | biological_process | BP |
| GO:0008565 | obsolete protein transporter activity | MF |
| GO:0012505 | endomembrane system | CC |
| GO:0015031 | protein transport | BP |
| GO:0015833 | peptide transport | BP |
| GO:0016020 | membrane | CC |
| GO:0017038 | protein import | BP |
| GO:0031090 | organelle membrane | CC |
| GO:0031965 | nuclear membrane | CC |
| GO:0031967 | organelle envelope | CC |
| GO:0031974 | membrane-enclosed lumen | CC |
| GO:0031975 | envelope | CC |
| GO:0031981 | nuclear lumen | CC |
| GO:0033036 | macromolecule localization | BP |
| GO:0033218 | amide binding | MF |
| GO:0033365 | protein localization to organelle | BP |
| GO:0034399 | nuclear periphery | CC |
| GO:0034504 | protein localization to nucleus | BP |
| GO:0034613 | protein localization | BP |
| GO:0042277 | peptide binding | MF |
| GO:0042886 | amide transport | BP |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043233 | organelle lumen | CC |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044428 | obsolete nuclear part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0045184 | establishment of protein localization | BP |
| GO:0046907 | intracellular transport | BP |
| GO:0051169 | nuclear transport | BP |
| GO:0051170 | import into nucleus | BP |
| GO:0051179 | localization | BP |
| GO:0051234 | establishment of localization | BP |
| GO:0051641 | cellular localization | BP |
| GO:0051649 | establishment of localization in cell | BP |
| GO:0070013 | intracellular organelle lumen | CC |
| GO:0070727 | cellular macromolecule localization | BP |
| GO:0071702 | organic substance transport | BP |
| GO:0071705 | nitrogen compound transport | BP |
| GO:0072594 | establishment of protein localization to organelle | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map03013 | RNA transport | RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation. |

