PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	gene-POTOM_037382 View in Genome Browser
Position	CM031987.1:3872573-3875953 (+) 3380bp
Gene Type	gene
Gene Description (Protein Product)	ATP binding
Organism	Populus tomentosa
Also AS	Potri.006G158600AT3G24530Potri.006G158600.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	gene-POTOM_043950 Peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine gene-POTOM_045138 Peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine gene-POTOM_059877 Belongs to the AAA ATPase family
Regulatory gene	gene-POTOM_000031 transcription repressor gene-POTOM_000108 Bromodomain-containing protein gene-POTOM_000126 ETHYLENE INSENSITIVE 3-like 3

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0000070	mitotic sister chromatid segregation	BP
GO:0000151	ubiquitin ligase complex	CC
GO:0000153	cytoplasmic ubiquitin ligase complex	CC
GO:0000166	nucleotide binding	MF
GO:0000226	microtubule cytoskeleton organization	BP
GO:0000228	nuclear chromosome	CC
GO:0000278	mitotic cell cycle	BP
GO:0000280	nuclear division	BP
GO:0000323	lytic vacuole	CC
GO:0000502	proteasome complex	CC
GO:0000731	DNA synthesis involved in DNA repair	BP
GO:0000785	chromatin	CC
GO:0000790	chromatin	CC
GO:0000819	sister chromatid segregation	BP
GO:0000835	ER ubiquitin ligase complex	CC
GO:0000836	Hrd1p ubiquitin ligase complex	CC
GO:0000837	Doa10p ubiquitin ligase complex	CC
GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex	CC
GO:0000902	cell morphogenesis	BP
GO:0000904	cell morphogenesis involved in differentiation	BP
GO:0001775	cell activation	BP
GO:0002020	protease binding	MF
GO:0002082	regulation of oxidative phosphorylation	BP
GO:0002165	instar larval or pupal development	BP
GO:0002252	immune effector process	BP
GO:0002263	cell activation involved in immune response	BP
GO:0002274	myeloid leukocyte activation	BP
GO:0002275	myeloid cell activation involved in immune response	BP
GO:0002283	neutrophil activation involved in immune response	BP
GO:0002366	leukocyte activation involved in immune response	BP
GO:0002376	immune system process	BP
GO:0002443	leukocyte mediated immunity	BP
GO:0002444	myeloid leukocyte mediated immunity	BP
GO:0002446	neutrophil mediated immunity	BP
GO:0003006	developmental process involved in reproduction	BP
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0005102	signaling receptor binding	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005524	ATP binding	MF
GO:0005575	cellular_component	CC
GO:0005576	extracellular region	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005694	chromosome	CC
GO:0005737	cytoplasm	CC
GO:0005739	mitochondrion	CC
GO:0005740	mitochondrial envelope	CC
GO:0005741	mitochondrial outer membrane	CC
GO:0005764	lysosome	CC
GO:0005766	primary lysosome	CC
GO:0005767	secondary lysosome	CC
GO:0005773	vacuole	CC
GO:0005775	vacuolar lumen	CC
GO:0005776	autophagosome	CC
GO:0005783	endoplasmic reticulum	CC
GO:0005789	endoplasmic reticulum membrane	CC
GO:0005811	lipid droplet	CC
GO:0005819	spindle	CC
GO:0005829	cytosol	CC
GO:0005856	cytoskeleton	CC
GO:0005937	mating projection	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006140	regulation of nucleotide metabolic process	BP
GO:0006163	purine nucleotide metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006281	DNA repair	BP
GO:0006301	postreplication repair	BP
GO:0006302	double-strand break repair	BP
GO:0006355	regulation of DNA-templated transcription	BP
GO:0006357	regulation of transcription by RNA polymerase II	BP
GO:0006401	RNA catabolic process	BP
GO:0006457	protein folding	BP
GO:0006464	protein modification process	BP
GO:0006486	protein glycosylation	BP
GO:0006487	protein N-linked glycosylation	BP
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006732	obsolete coenzyme metabolic process	BP
GO:0006733	obsolete oxidoreduction coenzyme metabolic process	BP
GO:0006734	NADH metabolic process	BP
GO:0006753	nucleoside phosphate metabolic process	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006810	transport	BP
GO:0006886	intracellular protein transport	BP
GO:0006887	exocytosis	BP
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	BP
GO:0006914	autophagy	BP
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	BP
GO:0006950	response to stress	BP
GO:0006955	immune response	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0006984	ER-nucleus signaling pathway	BP
GO:0006986	response to unfolded protein	BP
GO:0006991	response to sterol depletion	BP
GO:0006996	organelle organization	BP
GO:0007010	cytoskeleton organization	BP
GO:0007017	microtubule-based process	BP
GO:0007029	endoplasmic reticulum organization	BP
GO:0007030	Golgi organization	BP
GO:0007033	vacuole organization	BP
GO:0007034	vacuolar transport	BP
GO:0007040	lysosome organization	BP
GO:0007041	lysosomal transport	BP
GO:0007049	cell cycle	BP
GO:0007051	spindle organization	BP
GO:0007052	mitotic spindle organization	BP
GO:0007059	chromosome segregation	BP
GO:0007154	cell communication	BP
GO:0007163	establishment or maintenance of cell polarity	BP
GO:0007165	signal transduction	BP
GO:0007275	multicellular organism development	BP
GO:0007276	gamete generation	BP
GO:0007277	pole cell development	BP
GO:0007279	pole cell formation	BP
GO:0007317	regulation of pole plasm oskar mRNA localization	BP
GO:0007349	cellularization	BP
GO:0007399	nervous system development	BP
GO:0007552	metamorphosis	BP
GO:0007610	behavior	BP
GO:0007626	locomotory behavior	BP
GO:0008047	enzyme activator activity	MF
GO:0008104	protein localization	BP
GO:0008144	obsolete drug binding	MF
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008219	cell death	BP
GO:0008333	endosome to lysosome transport	BP
GO:0008608	attachment of spindle microtubules to kinetochore	BP
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009058	biosynthetic process	BP
GO:0009059	macromolecule biosynthetic process	BP
GO:0009100	glycoprotein metabolic process	BP
GO:0009101	glycoprotein biosynthetic process	BP
GO:0009109	obsolete coenzyme catabolic process	BP
GO:0009117	nucleotide metabolic process	BP
GO:0009123	nucleoside monophosphate metabolic process	BP
GO:0009126	purine nucleoside monophosphate metabolic process	BP
GO:0009141	nucleoside triphosphate metabolic process	BP
GO:0009144	purine nucleoside triphosphate metabolic process	BP
GO:0009150	purine ribonucleotide metabolic process	BP
GO:0009161	ribonucleoside monophosphate metabolic process	BP
GO:0009166	nucleotide catabolic process	BP
GO:0009167	purine ribonucleoside monophosphate metabolic process	BP
GO:0009199	ribonucleoside triphosphate metabolic process	BP
GO:0009205	purine ribonucleoside triphosphate metabolic process	BP
GO:0009259	ribonucleotide metabolic process	BP
GO:0009605	response to external stimulus	BP
GO:0009607	response to biotic stimulus	BP
GO:0009615	response to virus	BP
GO:0009653	anatomical structure morphogenesis	BP
GO:0009790	embryo development	BP
GO:0009791	post-embryonic development	BP
GO:0009792	embryo development ending in birth or egg hatching	BP
GO:0009886	post-embryonic animal morphogenesis	BP
GO:0009889	regulation of biosynthetic process	BP
GO:0009890	negative regulation of biosynthetic process	BP
GO:0009891	positive regulation of biosynthetic process	BP
GO:0009892	negative regulation of metabolic process	BP
GO:0009893	positive regulation of metabolic process	BP
GO:0009894	regulation of catabolic process	BP
GO:0009896	positive regulation of catabolic process	BP
GO:0009966	regulation of signal transduction	BP
GO:0009967	positive regulation of signal transduction	BP
GO:0009968	negative regulation of signal transduction	BP
GO:0009987	cellular process	BP
GO:0010033	response to organic substance	BP
GO:0010035	response to inorganic substance	BP
GO:0010038	response to metal ion	BP
GO:0010243	response to organonitrogen compound	BP
GO:0010256	endomembrane system organization	BP
GO:0010467	gene expression	BP
GO:0010468	regulation of gene expression	BP
GO:0010498	proteasomal protein catabolic process	BP
GO:0010556	regulation of macromolecule biosynthetic process	BP
GO:0010557	positive regulation of macromolecule biosynthetic process	BP
GO:0010558	negative regulation of macromolecule biosynthetic process	BP
GO:0010562	positive regulation of phosphorus metabolic process	BP
GO:0010604	positive regulation of macromolecule metabolic process	BP
GO:0010605	negative regulation of macromolecule metabolic process	BP
GO:0010623	programmed cell death involved in cell development	BP
GO:0010628	positive regulation of gene expression	BP
GO:0010638	positive regulation of organelle organization	BP
GO:0010646	regulation of cell communication	BP
GO:0010647	positive regulation of cell communication	BP
GO:0010648	negative regulation of cell communication	BP
GO:0010918	positive regulation of mitochondrial membrane potential	BP
GO:0010921	regulation of phosphatase activity	BP
GO:0010941	regulation of cell death	BP
GO:0010942	positive regulation of cell death	BP
GO:0010950	positive regulation of endopeptidase activity	BP
GO:0010952	positive regulation of peptidase activity	BP
GO:0012501	programmed cell death	BP
GO:0012505	endomembrane system	CC
GO:0015031	protein transport	BP
GO:0015630	microtubule cytoskeleton	CC
GO:0015833	peptide transport	BP
GO:0016020	membrane	CC
GO:0016032	viral process	BP
GO:0016043	cellular component organization	BP
GO:0016070	RNA metabolic process	BP
GO:0016072	rRNA metabolic process	BP
GO:0016075	rRNA catabolic process	BP
GO:0016192	vesicle-mediated transport	BP
GO:0016197	endosomal transport	BP
GO:0016236	macroautophagy	BP
GO:0016237	lysosomal microautophagy	BP
GO:0016320	endoplasmic reticulum membrane fusion	BP
GO:0016358	dendrite development	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016485	protein processing	BP
GO:0016504	peptidase activator activity	MF
GO:0016567	protein ubiquitination	BP
GO:0016579	protein deubiquitination	BP
GO:0016787	hydrolase activity	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0016887	ATP hydrolysis activity	MF
GO:0017076	purine nucleotide binding	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0017144	xenobiotic metabolic process	BP
GO:0018130	heterocycle biosynthetic process	BP
GO:0018193	peptidyl-amino acid modification	BP
GO:0018196	obsolete peptidyl-asparagine modification	BP
GO:0018279	protein N-linked glycosylation via asparagine	BP
GO:0019058	viral life cycle	BP
GO:0019079	viral genome replication	BP
GO:0019208	phosphatase regulator activity	MF
GO:0019219	regulation of nucleobase-containing compound metabolic process	BP
GO:0019220	regulation of phosphate metabolic process	BP
GO:0019222	regulation of metabolic process	BP
GO:0019362	pyridine nucleotide metabolic process	BP
GO:0019438	aromatic compound biosynthetic process	BP
GO:0019439	aromatic compound catabolic process	BP
GO:0019538	protein metabolic process	BP
GO:0019637	organophosphate metabolic process	BP
GO:0019674	NAD metabolic process	BP
GO:0019693	ribose phosphate metabolic process	BP
GO:0019725	cellular homeostasis	BP
GO:0019867	outer membrane	CC
GO:0019888	protein phosphatase regulator activity	MF
GO:0019899	enzyme binding	MF
GO:0019902	phosphatase binding	MF
GO:0019903	protein phosphatase binding	MF
GO:0019904	protein domain specific binding	MF
GO:0019941	modification-dependent protein catabolic process	BP
GO:0019953	sexual reproduction	BP
GO:0019985	translesion synthesis	BP
GO:0022008	neurogenesis	BP
GO:0022402	cell cycle process	BP
GO:0022411	cellular component disassembly	BP
GO:0022412	cellular process involved in reproduction in multicellular organism	BP
GO:0022414	reproductive process	BP
GO:0022607	cellular component assembly	BP
GO:0023051	regulation of signaling	BP
GO:0023052	signaling	BP
GO:0023056	positive regulation of signaling	BP
GO:0023057	negative regulation of signaling	BP
GO:0030030	cell projection organization	BP
GO:0030111	regulation of Wnt signaling pathway	BP
GO:0030141	secretory granule	CC
GO:0030154	cell differentiation	BP
GO:0030162	regulation of proteolysis	BP
GO:0030163	protein catabolic process	BP
GO:0030177	positive regulation of Wnt signaling pathway	BP
GO:0030178	negative regulation of Wnt signaling pathway	BP
GO:0030182	neuron differentiation	BP
GO:0030234	enzyme regulator activity	MF
GO:0030427	site of polarized growth	CC
GO:0030433	ubiquitin-dependent ERAD pathway	BP
GO:0030554	adenyl nucleotide binding	MF
GO:0030808	regulation of nucleotide biosynthetic process	BP
GO:0030810	positive regulation of nucleotide biosynthetic process	BP
GO:0030968	endoplasmic reticulum unfolded protein response	BP
GO:0030970	retrograde protein transport, ER to cytosol	BP
GO:0031056	regulation of histone modification	BP
GO:0031058	positive regulation of histone modification	BP
GO:0031090	organelle membrane	CC
GO:0031134	sister chromatid biorientation	BP
GO:0031175	neuron projection development	BP
GO:0031323	regulation of cellular metabolic process	BP
GO:0031324	negative regulation of cellular metabolic process	BP
GO:0031325	positive regulation of cellular metabolic process	BP
GO:0031326	regulation of cellular biosynthetic process	BP
GO:0031327	negative regulation of cellular biosynthetic process	BP
GO:0031328	positive regulation of cellular biosynthetic process	BP
GO:0031329	regulation of cellular catabolic process	BP
GO:0031331	positive regulation of cellular catabolic process	BP
GO:0031334	positive regulation of protein-containing complex assembly	BP
GO:0031396	regulation of protein ubiquitination	BP
GO:0031398	positive regulation of protein ubiquitination	BP
GO:0031399	regulation of protein modification process	BP
GO:0031401	positive regulation of protein modification process	BP
GO:0031410	cytoplasmic vesicle	CC
GO:0031593	polyubiquitin modification-dependent protein binding	MF
GO:0031625	ubiquitin protein ligase binding	MF
GO:0031966	mitochondrial membrane	CC
GO:0031967	organelle envelope	CC
GO:0031968	organelle outer membrane	CC
GO:0031974	membrane-enclosed lumen	CC
GO:0031975	envelope	CC
GO:0031981	nuclear lumen	CC
GO:0031982	vesicle	CC
GO:0031983	vesicle lumen	CC
GO:0031984	organelle subcompartment	CC
GO:0032182	ubiquitin-like protein binding	MF
GO:0032268	regulation of protein metabolic process	BP
GO:0032270	positive regulation of protein metabolic process	BP
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	BP
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	BP
GO:0032446	protein modification by small protein conjugation	BP
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0032504	multicellular organism reproduction	BP
GO:0032509	endosome transport via multivesicular body sorting pathway	BP
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	BP
GO:0032527	protein exit from endoplasmic reticulum	BP
GO:0032553	ribonucleotide binding	MF
GO:0032555	purine ribonucleotide binding	MF
GO:0032559	adenyl ribonucleotide binding	MF
GO:0032879	regulation of localization	BP
GO:0032880	regulation of protein localization	BP
GO:0032933	SREBP signaling pathway	BP
GO:0032940	secretion by cell	BP
GO:0032984	protein-containing complex disassembly	BP
GO:0032989	cellular component morphogenesis	BP
GO:0032990	cell part morphogenesis	BP
GO:0032991	protein-containing complex	CC
GO:0033036	macromolecule localization	BP
GO:0033043	regulation of organelle organization	BP
GO:0033044	regulation of chromosome organization	BP
GO:0033182	regulation of histone ubiquitination	BP
GO:0033184	positive regulation of histone ubiquitination	BP
GO:0033365	protein localization to organelle	BP
GO:0033554	cellular response to stress	BP
GO:0034067	protein localization to Golgi apparatus	BP
GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	CC
GO:0034214	protein hexamerization	BP
GO:0034404	nucleobase-containing small molecule biosynthetic process	BP
GO:0034517	ribophagy	BP
GO:0034613	protein localization	BP
GO:0034620	cellular response to unfolded protein	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034645	cellular macromolecule biosynthetic process	BP
GO:0034654	nucleobase-containing compound biosynthetic process	BP
GO:0034655	nucleobase-containing compound catabolic process	BP
GO:0034660	ncRNA metabolic process	BP
GO:0034661	ncRNA catabolic process	BP
GO:0034727	piecemeal microautophagy of the nucleus	BP
GO:0034774	secretory granule lumen	CC
GO:0034976	response to endoplasmic reticulum stress	BP
GO:0035069	larval midgut histolysis	BP
GO:0035096	larval midgut cell programmed cell death	BP
GO:0035103	sterol regulatory element binding protein cleavage	BP
GO:0035303	regulation of dephosphorylation	BP
GO:0035304	regulation of protein dephosphorylation	BP
GO:0035578	azurophil granule lumen	CC
GO:0035639	purine ribonucleoside triphosphate binding	MF
GO:0035770	ribonucleoprotein granule	CC
GO:0035800	deubiquitinase activator activity	MF
GO:0035861	site of double-strand break	CC
GO:0035966	response to topologically incorrect protein	BP
GO:0035967	cellular response to topologically incorrect protein	BP
GO:0035973	aggrephagy	BP
GO:0036094	small molecule binding	MF
GO:0036211	protein modification process	BP
GO:0036230	granulocyte activation	BP
GO:0036266	Cdc48p-Npl4p-Vms1p AAA ATPase complex	CC
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	MF
GO:0036464	cytoplasmic ribonucleoprotein granule	CC
GO:0036503	ERAD pathway	BP
GO:0036513	Derlin-1 retrotranslocation complex	CC
GO:0042119	neutrophil activation	BP
GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network	CC
GO:0042176	regulation of protein catabolic process	BP
GO:0042221	response to chemical	BP
GO:0042287	MHC protein binding	MF
GO:0042288	MHC class I protein binding	MF
GO:0042325	regulation of phosphorylation	BP
GO:0042327	positive regulation of phosphorylation	BP
GO:0042391	regulation of membrane potential	BP
GO:0042582	azurophil granule	CC
GO:0042592	homeostatic process	BP
GO:0042726	flavin-containing compound metabolic process	BP
GO:0042728	flavin-containing compound catabolic process	BP
GO:0042802	identical protein binding	MF
GO:0042886	amide transport	BP
GO:0042981	regulation of apoptotic process	BP
GO:0042995	cell projection	CC
GO:0043009	chordate embryonic development	BP
GO:0043065	positive regulation of apoptotic process	BP
GO:0043067	regulation of programmed cell death	BP
GO:0043068	positive regulation of programmed cell death	BP
GO:0043085	positive regulation of catalytic activity	BP
GO:0043086	negative regulation of catalytic activity	BP
GO:0043130	ubiquitin binding	MF
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BP
GO:0043167	ion binding	MF
GO:0043168	anion binding	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043186	P granule	CC
GO:0043207	response to external biotic stimulus	BP
GO:0043209	myelin sheath	CC
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043254	regulation of protein-containing complex assembly	BP
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	BP
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	BP
GO:0043299	leukocyte degranulation	BP
GO:0043312	neutrophil degranulation	BP
GO:0043332	mating projection tip	CC
GO:0043412	macromolecule modification	BP
GO:0043413	macromolecule glycosylation	BP
GO:0043457	regulation of cellular respiration	BP
GO:0043467	regulation of generation of precursor metabolites and energy	BP
GO:0043523	regulation of neuron apoptotic process	BP
GO:0043525	positive regulation of neuron apoptotic process	BP
GO:0043531	ADP binding	MF
GO:0043624	protein-containing complex disassembly	BP
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0043666	regulation of phosphoprotein phosphatase activity	BP
GO:0043900	obsolete regulation of multi-organism process	BP
GO:0043902	obsolete positive regulation of multi-organism process	BP
GO:0043903	regulation of biological process involved in symbiotic interaction	BP
GO:0043933	protein-containing complex organization	BP
GO:0044085	cellular component biogenesis	BP
GO:0044087	regulation of cellular component biogenesis	BP
GO:0044089	positive regulation of cellular component biogenesis	BP
GO:0044092	negative regulation of molecular function	BP
GO:0044093	positive regulation of molecular function	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044270	cellular nitrogen compound catabolic process	BP
GO:0044271	cellular nitrogen compound biosynthetic process	BP
GO:0044281	small molecule metabolic process	BP
GO:0044283	small molecule biosynthetic process	BP
GO:0044389	ubiquitin-like protein ligase binding	MF
GO:0044403	biological process involved in symbiotic interaction	BP
GO:0044419	biological process involved in interspecies interaction between organisms	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044425	obsolete membrane part	CC
GO:0044427	obsolete chromosomal part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044429	obsolete mitochondrial part	CC
GO:0044430	obsolete cytoskeletal part	CC
GO:0044432	obsolete endoplasmic reticulum part	CC
GO:0044433	obsolete cytoplasmic vesicle part	CC
GO:0044437	obsolete vacuolar part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044454	obsolete nuclear chromosome part	CC
GO:0044455	obsolete mitochondrial membrane part	CC
GO:0044463	obsolete cell projection part	CC
GO:0044464	obsolete cell part	CC
GO:0044703	multi-organism reproductive process	BP
GO:0044754	autolysosome	CC
GO:0044804	autophagy of nucleus	BP
GO:0044877	protein-containing complex binding	MF
GO:0045055	regulated exocytosis	BP
GO:0045169	fusome	CC
GO:0045184	establishment of protein localization	BP
GO:0045321	leukocyte activation	BP
GO:0045495	pole plasm	CC
GO:0045595	regulation of cell differentiation	BP
GO:0045732	positive regulation of protein catabolic process	BP
GO:0045838	positive regulation of membrane potential	BP
GO:0045862	positive regulation of proteolysis	BP
GO:0045893	positive regulation of DNA-templated transcription	BP
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	BP
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	BP
GO:0045937	positive regulation of phosphate metabolic process	BP
GO:0045944	positive regulation of transcription by RNA polymerase II	BP
GO:0045981	positive regulation of nucleotide metabolic process	BP
GO:0045995	regulation of embryonic development	BP
GO:0046034	ATP metabolic process	BP
GO:0046434	organophosphate catabolic process	BP
GO:0046483	heterocycle metabolic process	BP
GO:0046496	nicotinamide nucleotide metabolic process	BP
GO:0046596	regulation of viral entry into host cell	BP
GO:0046598	positive regulation of viral entry into host cell	BP
GO:0046686	response to cadmium ion	BP
GO:0046700	heterocycle catabolic process	BP
GO:0046716	muscle cell cellular homeostasis	BP
GO:0046903	secretion	BP
GO:0046907	intracellular transport	BP
GO:0048193	Golgi vesicle transport	BP
GO:0048284	organelle fusion	BP
GO:0048285	organelle fission	BP
GO:0048468	cell development	BP
GO:0048471	perinuclear region of cytoplasm	CC
GO:0048518	positive regulation of biological process	BP
GO:0048519	negative regulation of biological process	BP
GO:0048522	positive regulation of cellular process	BP
GO:0048523	negative regulation of cellular process	BP
GO:0048524	positive regulation of viral process	BP
GO:0048583	regulation of response to stimulus	BP
GO:0048584	positive regulation of response to stimulus	BP
GO:0048585	negative regulation of response to stimulus	BP
GO:0048609	multicellular organismal reproductive process	BP
GO:0048646	anatomical structure formation involved in morphogenesis	BP
GO:0048666	neuron development	BP
GO:0048667	cell morphogenesis involved in neuron differentiation	BP
GO:0048699	generation of neurons	BP
GO:0048707	instar larval or pupal morphogenesis	BP
GO:0048731	system development	BP
GO:0048812	neuron projection morphogenesis	BP
GO:0048813	dendrite morphogenesis	BP
GO:0048856	anatomical structure development	BP
GO:0048858	cell projection morphogenesis	BP
GO:0048869	cellular developmental process	BP
GO:0050789	regulation of biological process	BP
GO:0050790	regulation of catalytic activity	BP
GO:0050792	regulation of viral process	BP
GO:0050793	regulation of developmental process	BP
GO:0050794	regulation of cellular process	BP
GO:0050896	response to stimulus	BP
GO:0051052	regulation of DNA metabolic process	BP
GO:0051053	negative regulation of DNA metabolic process	BP
GO:0051128	regulation of cellular component organization	BP
GO:0051130	positive regulation of cellular component organization	BP
GO:0051171	regulation of nitrogen compound metabolic process	BP
GO:0051172	negative regulation of nitrogen compound metabolic process	BP
GO:0051173	positive regulation of nitrogen compound metabolic process	BP
GO:0051174	regulation of phosphorus metabolic process	BP
GO:0051179	localization	BP
GO:0051186	obsolete cofactor metabolic process	BP
GO:0051187	obsolete cofactor catabolic process	BP
GO:0051228	mitotic spindle disassembly	BP
GO:0051230	spindle disassembly	BP
GO:0051233	spindle midzone	CC
GO:0051234	establishment of localization	BP
GO:0051239	regulation of multicellular organismal process	BP
GO:0051246	regulation of protein metabolic process	BP
GO:0051247	positive regulation of protein metabolic process	BP
GO:0051252	regulation of RNA metabolic process	BP
GO:0051254	positive regulation of RNA metabolic process	BP
GO:0051259	protein complex oligomerization	BP
GO:0051260	protein homooligomerization	BP
GO:0051276	chromosome organization	BP
GO:0051286	cell tip	CC
GO:0051304	chromosome separation	BP
GO:0051306	mitotic sister chromatid separation	BP
GO:0051336	regulation of hydrolase activity	BP
GO:0051338	regulation of transferase activity	BP
GO:0051345	positive regulation of hydrolase activity	BP
GO:0051348	negative regulation of transferase activity	BP
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0051604	protein maturation	BP
GO:0051640	organelle localization	BP
GO:0051641	cellular localization	BP
GO:0051643	endoplasmic reticulum localization	BP
GO:0051649	establishment of localization in cell	BP
GO:0051656	establishment of organelle localization	BP
GO:0051686	establishment of ER localization	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051707	response to other organism	BP
GO:0051716	cellular response to stimulus	BP
GO:0051788	response to misfolded protein	BP
GO:0051881	regulation of mitochondrial membrane potential	BP
GO:0051972	regulation of telomerase activity	BP
GO:0051974	negative regulation of telomerase activity	BP
GO:0052547	regulation of peptidase activity	BP
GO:0052548	regulation of endopeptidase activity	BP
GO:0055085	transmembrane transport	BP
GO:0055086	nucleobase-containing small molecule metabolic process	BP
GO:0060033	anatomical structure regression	BP
GO:0060090	molecular adaptor activity	MF
GO:0060205	cytoplasmic vesicle lumen	CC
GO:0060249	anatomical structure homeostasis	BP
GO:0060255	regulation of macromolecule metabolic process	BP
GO:0060281	regulation of oocyte development	BP
GO:0060284	regulation of cell development	BP
GO:0060293	germ plasm	CC
GO:0060341	regulation of cellular localization	BP
GO:0060828	regulation of canonical Wnt signaling pathway	BP
GO:0061024	membrane organization	BP
GO:0061025	membrane fusion	BP
GO:0061134	peptidase regulator activity	MF
GO:0061136	regulation of proteasomal protein catabolic process	BP
GO:0061163	endoplasmic reticulum polarization	BP
GO:0061164	endoplasmic reticulum polarization	BP
GO:0061165	endoplasmic reticulum polarization	BP
GO:0061166	endoplasmic reticulum polarization	BP
GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control	BP
GO:0061912	selective autophagy	BP
GO:0061919	process utilizing autophagic mechanism	BP
GO:0062012	regulation of small molecule metabolic process	BP
GO:0062013	positive regulation of small molecule metabolic process	BP
GO:0065003	protein-containing complex assembly	BP
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0065009	regulation of molecular function	BP
GO:0070013	intracellular organelle lumen	CC
GO:0070085	glycosylation	BP
GO:0070646	protein modification by small protein removal	BP
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0070651	nonfunctional rRNA decay	BP
GO:0070727	cellular macromolecule localization	BP
GO:0070841	inclusion body assembly	BP
GO:0070842	aggresome assembly	BP
GO:0070887	cellular response to chemical stimulus	BP
GO:0070987	error-free translesion synthesis	BP
GO:0071218	cellular response to misfolded protein	BP
GO:0071241	cellular response to inorganic substance	BP
GO:0071248	cellular response to metal ion	BP
GO:0071276	cellular response to cadmium ion	BP
GO:0071310	cellular response to organic substance	BP
GO:0071501	cellular response to sterol depletion	BP
GO:0071629	cytoplasm protein quality control by the ubiquitin-proteasome system	BP
GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	BP
GO:0071702	organic substance transport	BP
GO:0071704	organic substance metabolic process	BP
GO:0071705	nitrogen compound transport	BP
GO:0071712	ER-associated misfolded protein catabolic process	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0071897	DNA biosynthetic process	BP
GO:0071985	multivesicular body sorting pathway	BP
GO:0072387	flavin adenine dinucleotide metabolic process	BP
GO:0072389	flavin adenine dinucleotide catabolic process	BP
GO:0072521	purine-containing compound metabolic process	BP
GO:0072524	pyridine-containing compound metabolic process	BP
GO:0072671	mitochondria-associated ubiquitin-dependent protein catabolic process	BP
GO:0072686	mitotic spindle	CC
GO:0080090	regulation of primary metabolic process	BP
GO:0080171	lytic vacuole organization	BP
GO:0090085	regulation of protein deubiquitination	BP
GO:0090090	negative regulation of canonical Wnt signaling pathway	BP
GO:0090174	organelle membrane fusion	BP
GO:0090263	positive regulation of canonical Wnt signaling pathway	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090734	site of DNA damage	CC
GO:0097159	organic cyclic compound binding	MF
GO:0097352	autophagosome maturation	BP
GO:0097367	carbohydrate derivative binding	MF
GO:0097708	intracellular vesicle	CC
GO:0098586	cellular response to virus	BP
GO:0098588	bounding membrane of organelle	CC
GO:0098772	molecular function regulator activity	MF
GO:0098796	membrane protein complex	CC
GO:0098798	mitochondrial protein-containing complex	CC
GO:0098799	outer mitochondrial membrane protein complex	CC
GO:0098805	membrane	CC
GO:0098813	nuclear chromosome segregation	BP
GO:0098827	endoplasmic reticulum subcompartment	CC
GO:0099503	secretory vesicle	CC
GO:0101002	ficolin-1-rich granule	CC
GO:0120025	plasma membrane bounded cell projection	CC
GO:0120036	plasma membrane bounded cell projection organization	BP
GO:0120038	obsolete plasma membrane bounded cell projection part	CC
GO:0120039	plasma membrane bounded cell projection morphogenesis	BP
GO:0140014	mitotic nuclear division	BP
GO:0140030	modification-dependent protein binding	MF
GO:1900180	regulation of protein localization to nucleus	BP
GO:1900182	positive regulation of protein localization to nucleus	BP
GO:1900371	regulation of purine nucleotide biosynthetic process	BP
GO:1900373	positive regulation of purine nucleotide biosynthetic process	BP
GO:1900542	regulation of purine nucleotide metabolic process	BP
GO:1900544	positive regulation of purine nucleotide metabolic process	BP
GO:1901135	carbohydrate derivative metabolic process	BP
GO:1901137	carbohydrate derivative biosynthetic process	BP
GO:1901214	regulation of neuron death	BP
GO:1901216	positive regulation of neuron death	BP
GO:1901265	nucleoside phosphate binding	MF
GO:1901292	nucleoside phosphate catabolic process	BP
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901361	organic cyclic compound catabolic process	BP
GO:1901362	organic cyclic compound biosynthetic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901566	organonitrogen compound biosynthetic process	BP
GO:1901575	organic substance catabolic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1901698	response to nitrogen compound	BP
GO:1901800	positive regulation of proteasomal protein catabolic process	BP
GO:1902275	regulation of chromatin organization	BP
GO:1902494	catalytic complex	CC
GO:1902680	positive regulation of RNA biosynthetic process	BP
GO:1902850	microtubule cytoskeleton organization involved in mitosis	BP
GO:1902875	regulation of embryonic pattern specification	BP
GO:1903003	positive regulation of protein deubiquitination	BP
GO:1903004	regulation of protein K63-linked deubiquitination	BP
GO:1903006	positive regulation of protein K63-linked deubiquitination	BP
GO:1903007	positive regulation of Lys63-specific deubiquitinase activity	BP
GO:1903008	organelle disassembly	BP
GO:1903047	mitotic cell cycle process	BP
GO:1903050	regulation of proteolysis involved in protein catabolic process	BP
GO:1903052	positive regulation of proteolysis involved in protein catabolic process	BP
GO:1903320	regulation of protein modification by small protein conjugation or removal	BP
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	BP
GO:1903362	regulation of protein catabolic process	BP
GO:1903364	positive regulation of protein catabolic process	BP
GO:1903429	regulation of cell maturation	BP
GO:1903506	regulation of nucleic acid-templated transcription	BP
GO:1903508	positive regulation of nucleic acid-templated transcription	BP
GO:1903513	endoplasmic reticulum to cytosol transport	BP
GO:1903578	regulation of ATP metabolic process	BP
GO:1903580	positive regulation of ATP metabolic process	BP
GO:1903715	regulation of aerobic respiration	BP
GO:1903827	regulation of protein localization	BP
GO:1903829	positive regulation of protein localization	BP
GO:1903862	positive regulation of oxidative phosphorylation	BP
GO:1903900	regulation of viral life cycle	BP
GO:1903902	positive regulation of viral life cycle	BP
GO:1904288	BAT3 complex binding	MF
GO:1904580	regulation of intracellular mRNA localization	BP
GO:1904813	ficolin-1-rich granule lumen	CC
GO:1904949	ATPase complex	CC
GO:1905269	positive regulation of chromatin organization	BP
GO:1905368	peptidase complex	CC
GO:1905369	endopeptidase complex	CC
GO:1905879	regulation of oogenesis	BP
GO:1990023	mitotic spindle midzone	CC
GO:1990112	RQC complex	CC
GO:1990116	ribosome-associated ubiquitin-dependent protein catabolic process	BP
GO:1990171	SCF complex disassembly in response to cadmium stress	BP
GO:1990234	transferase complex	CC
GO:1990381	ubiquitin-specific protease binding	MF
GO:1990730	VCP-NSFL1C complex	CC
GO:1990904	ribonucleoprotein complex	CC
GO:2000026	regulation of multicellular organismal development	BP
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	BP
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	BP
GO:2000112	regulation of cellular macromolecule biosynthetic process	BP
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	BP
GO:2000116	regulation of cysteine-type endopeptidase activity	BP
GO:2000152	regulation of ubiquitin-specific protease activity	BP
GO:2000158	positive regulation of ubiquitin-specific protease activity	BP
GO:2000241	regulation of reproductive process	BP
GO:2000278	regulation of DNA biosynthetic process	BP
GO:2000279	negative regulation of DNA biosynthetic process	BP
GO:2001056	positive regulation of cysteine-type endopeptidase activity	BP
GO:2001141	regulation of RNA biosynthetic process	BP
GO:2001166	regulation of histone H2B ubiquitination	BP
GO:2001168	positive regulation of histone H2B ubiquitination	BP
GO:2001169	regulation of ATP biosynthetic process	BP
GO:2001171	positive regulation of ATP biosynthetic process	BP
GO:2001252	positive regulation of chromosome organization	BP

KEGG Term	Name	Description
map04141	Protein processing in endoplasmic reticulum	The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.