Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-POTOM_046250
View in Genome Browser
Position
CM031994.1:2648328-2650296 (+)
1968bp
Gene Type
gene
Gene Description (Protein Product)
NEDD8 transferase activity
Organism
Populus tomentosa
Also AS Potri.014G041466Potri.014G041466.v4.1

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-POTOM_060025 Belongs to the cullin family
gene-POTOM_050709 SUMO-activating enzyme subunit
gene-POTOM_049610 SUMO-activating enzyme subunit
Regulatory gene
gene-POTOM_000682 Dof zinc finger protein
gene-POTOM_004231 Dof zinc finger protein
gene-POTOM_005400 Dof zinc finger protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004842 ubiquitin-protein transferase activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0006464 protein modification process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008589 regulation of smoothened signaling pathway BP
GO:0009966 regulation of signal transduction BP
GO:0009968 negative regulation of signal transduction BP
GO:0009987 cellular process BP
GO:0010646 regulation of cell communication BP
GO:0010648 negative regulation of cell communication BP
GO:0010941 regulation of cell death BP
GO:0010942 positive regulation of cell death BP
GO:0016567 protein ubiquitination BP
GO:0016740 transferase activity MF
GO:0019538 protein metabolic process BP
GO:0019787 ubiquitin-like protein transferase activity MF
GO:0019788 NEDD8 transferase activity MF
GO:0023051 regulation of signaling BP
GO:0023057 negative regulation of signaling BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032446 protein modification by small protein conjugation BP
GO:0036211 protein modification process BP
GO:0042981 regulation of apoptotic process BP
GO:0043065 positive regulation of apoptotic process BP
GO:0043067 regulation of programmed cell death BP
GO:0043068 positive regulation of programmed cell death BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043412 macromolecule modification BP
GO:0043523 regulation of neuron apoptotic process BP
GO:0043525 positive regulation of neuron apoptotic process BP
GO:0043687 post-translational protein modification BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045116 protein neddylation BP
GO:0045879 negative regulation of smoothened signaling pathway BP
GO:0048518 positive regulation of biological process BP
GO:0048519 negative regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0048523 negative regulation of cellular process BP
GO:0048583 regulation of response to stimulus BP
GO:0048585 negative regulation of response to stimulus BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0061650 ubiquitin-like protein conjugating enzyme activity MF
GO:0061654 NEDD8 conjugating enzyme activity MF
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0070647 protein modification by small protein conjugation or removal BP
GO:0071704 organic substance metabolic process BP
GO:0140096 catalytic activity, acting on a protein MF
GO:1901214 regulation of neuron death BP
GO:1901216 positive regulation of neuron death BP
GO:1901564 organonitrogen compound metabolic process BP
KEGG Term Name Description
map04120 Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map01100 Metabolic pathways -
map00770 Pantothenate and CoA biosynthesis -
map00520 Amino sugar and nucleotide sugar metabolism -
map00290 Valine, leucine and isoleucine biosynthesis -