Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-POTOM_049952
View in Genome Browser
Position
CM031996.1:12206315-12208670 (-)
2355bp
Gene Type
gene
Gene Description (Protein Product)
Forkhead associated domain
Organism
Populus tomentosa
Also AS Potri.015G148300AT3G02680Potri.015G148300.v4.1

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-POTOM_061561 DNA topoisomerase 2-binding protein
gene-POTOM_061382 DNA topoisomerase 2-binding protein
gene-POTOM_062217 DNA topoisomerase 2-binding protein
Regulatory gene
gene-POTOM_000108 Bromodomain-containing protein
gene-POTOM_000145 AP2-like ethylene-responsive transcription factor
gene-POTOM_000620 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000075 cell cycle checkpoint signaling BP
GO:0000077 DNA damage checkpoint signaling BP
GO:0000228 nuclear chromosome CC
GO:0000278 mitotic cell cycle BP
GO:0000280 nuclear division BP
GO:0000723 telomere maintenance BP
GO:0000724 double-strand break repair via homologous recombination BP
GO:0000725 recombinational repair BP
GO:0000781 chromosome, telomeric region CC
GO:0000784 chromosome, telomeric region CC
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003684 damaged DNA binding MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005694 chromosome CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006310 DNA recombination BP
GO:0006312 mitotic recombination BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0007093 mitotic cell cycle checkpoint signaling BP
GO:0007095 mitotic G2 DNA damage checkpoint signaling BP
GO:0007127 meiosis I BP
GO:0007131 reciprocal meiotic recombination BP
GO:0007154 cell communication BP
GO:0007165 signal transduction BP
GO:0007346 regulation of mitotic cell cycle BP
GO:0008134 transcription factor binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009314 response to radiation BP
GO:0009628 response to abiotic stimulus BP
GO:0009987 cellular process BP
GO:0010212 response to ionizing radiation BP
GO:0010389 regulation of G2/M transition of mitotic cell cycle BP
GO:0010564 regulation of cell cycle process BP
GO:0010948 negative regulation of cell cycle process BP
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle BP
GO:0016043 cellular component organization BP
GO:0016233 telomere capping BP
GO:0016234 inclusion body CC
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0023052 signaling BP
GO:0030870 Mre11 complex CC
GO:0031570 DNA integrity checkpoint signaling BP
GO:0031572 mitotic G2 DNA damage checkpoint signaling BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032200 telomere organization BP
GO:0032392 DNA geometric change BP
GO:0032508 DNA duplex unwinding BP
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035556 intracellular signal transduction BP
GO:0035825 homologous recombination BP
GO:0042127 regulation of cell population proliferation BP
GO:0042405 nuclear inclusion body CC
GO:0042592 homeostatic process BP
GO:0042770 signal transduction in response to DNA damage BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044427 obsolete chromosomal part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044454 obsolete nuclear chromosome part CC
GO:0044464 obsolete cell part CC
GO:0044773 mitotic DNA damage checkpoint signaling BP
GO:0044774 mitotic DNA integrity checkpoint signaling BP
GO:0044818 mitotic G2/M transition checkpoint BP
GO:0045786 negative regulation of cell cycle BP
GO:0045930 negative regulation of mitotic cell cycle BP
GO:0046483 heterocycle metabolic process BP
GO:0047485 obsolete protein N-terminus binding MF
GO:0048145 regulation of fibroblast proliferation BP
GO:0048285 organelle fission BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051276 chromosome organization BP
GO:0051321 meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0051726 regulation of cell cycle BP
GO:0060249 anatomical structure homeostasis BP
GO:0061982 meiosis I cell cycle process BP
GO:0065007 biological regulation BP
GO:0065008 regulation of biological quality BP
GO:0070013 intracellular organelle lumen CC
GO:0071103 DNA conformation change BP
GO:0071214 cellular response to abiotic stimulus BP
GO:0071478 cellular response to radiation BP
GO:0071479 cellular response to ionizing radiation BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:0098687 chromosomal region CC
GO:0104004 cellular response to environmental stimulus BP
GO:0140013 meiotic nuclear division BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901987 regulation of cell cycle phase transition BP
GO:1901988 negative regulation of cell cycle phase transition BP
GO:1901990 regulation of mitotic cell cycle phase transition BP
GO:1901991 negative regulation of mitotic cell cycle phase transition BP
GO:1902749 regulation of cell cycle G2/M phase transition BP
GO:1902750 negative regulation of cell cycle G2/M phase transition BP
GO:1903046 meiotic cell cycle process BP
GO:1903047 mitotic cell cycle process BP
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.