Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-POTOM_051820
View in Genome Browser
Position
CM031998.1:8791487-8795745 (+)
4258bp
Gene Type
gene
Gene Description (Protein Product)
Hsp70 nucleotide exchange factor
Organism
Populus tomentosa
Also AS Potri.016G100500AT3G09350Potri.016G100500.v4.1

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-POTOM_052293 Heat shock 70 kDa protein
gene-POTOM_060298 Belongs to the heat shock protein 70 family
gene-POTOM_056512 Belongs to the bacterial ribosomal protein bL36 family
Regulatory gene
gene-POTOM_000368 ZINC FINGER protein
gene-POTOM_000682 Dof zinc finger protein
gene-POTOM_001027 ZINC FINGER protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0004857 enzyme inhibitor activity MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0008150 biological_process BP
GO:0009893 positive regulation of metabolic process BP
GO:0009894 regulation of catabolic process BP
GO:0009896 positive regulation of catabolic process BP
GO:0010604 positive regulation of macromolecule metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019899 enzyme binding MF
GO:0030162 regulation of proteolysis BP
GO:0030234 enzyme regulator activity MF
GO:0031323 regulation of cellular metabolic process BP
GO:0031325 positive regulation of cellular metabolic process BP
GO:0031329 regulation of cellular catabolic process BP
GO:0031331 positive regulation of cellular catabolic process BP
GO:0031396 regulation of protein ubiquitination BP
GO:0031398 positive regulation of protein ubiquitination BP
GO:0031399 regulation of protein modification process BP
GO:0031401 positive regulation of protein modification process BP
GO:0031625 ubiquitin protein ligase binding MF
GO:0032268 regulation of protein metabolic process BP
GO:0032270 positive regulation of protein metabolic process BP
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process BP
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process BP
GO:0042176 regulation of protein catabolic process BP
GO:0043086 negative regulation of catalytic activity BP
GO:0044092 negative regulation of molecular function BP
GO:0044389 ubiquitin-like protein ligase binding MF
GO:0045732 positive regulation of protein catabolic process BP
GO:0045862 positive regulation of proteolysis BP
GO:0048518 positive regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050790 regulation of catalytic activity BP
GO:0050794 regulation of cellular process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051173 positive regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051247 positive regulation of protein metabolic process BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0061136 regulation of proteasomal protein catabolic process BP
GO:0065007 biological regulation BP
GO:0065009 regulation of molecular function BP
GO:0080090 regulation of primary metabolic process BP
GO:0098772 molecular function regulator activity MF
GO:1901800 positive regulation of proteasomal protein catabolic process BP
GO:1903050 regulation of proteolysis involved in protein catabolic process BP
GO:1903052 positive regulation of proteolysis involved in protein catabolic process BP
GO:1903320 regulation of protein modification by small protein conjugation or removal BP
GO:1903322 positive regulation of protein modification by small protein conjugation or removal BP
GO:1903362 regulation of protein catabolic process BP
GO:1903364 positive regulation of protein catabolic process BP
GO:2000058 regulation of ubiquitin-dependent protein catabolic process BP
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process BP
KEGG Term Name Description
map04141 Protein processing in endoplasmic reticulum The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.