PPGR - Gene Detail

Gene ID	gene-POTOM_061097 View in Genome Browser
Position	JAAWWB010001236.1:22832-24741 (+) 1909bp
Gene Type	gene
Gene Description (Protein Product)	RNA recognition motif
Organism	Populus tomentosa
Also AS	Potri.008G182500AT1G13190Potri.008G182500.v4.1

upstream:

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Protein-protein interaction (PPI)

gene-POTOM_062237 Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly

gene-POTOM_062160 DEAD-box ATP-dependent RNA helicase

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Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003676	nucleic acid binding	MF
GO:0003723	RNA binding	MF
GO:0003729	mRNA binding	MF
GO:0005488	binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0044424	obsolete intracellular part	CC
GO:0044464	obsolete cell part	CC
GO:0097159	organic cyclic compound binding	MF
GO:1901363	heterocyclic compound binding	MF

KEGG Term	Name	Description
map03015	mRNA surveillance pathway	The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins.