Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
Potra2n5c10810
View in Genome Browser
Position
chr5:2063589-2068119 (-)
4530bp
Gene Type
gene
Gene Description (Protein Product)
DNA-3-methyladenine glycosylase
Organism
Populus tremula
Also AS Potri.005G227700AT1G75230Potri.005G227700.v4.1

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Potra2n7c16421 DNA-3-methyladenine glycosylase
Potra2n6c15013 DNA-(Apurinic or apyrimidinic site) lyase
Potra2n6c15013 Glycosyltransferase-like
Regulatory gene
Potra2n10c20715 transcription factor
Potra2n10c20775 Transcription factor
Potra2n10c20932 Zinc-finger homeodomain protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003684 damaged DNA binding MF
GO:0003824 catalytic activity MF
GO:0003905 alkylbase DNA N-glycosylase activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006284 base-excision repair BP
GO:0006285 base-excision repair, AP site formation BP
GO:0006304 DNA modification BP
GO:0006307 DNA dealkylation involved in DNA repair BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008725 DNA-3-methyladenine glycosylase activity MF
GO:0009987 cellular process BP
GO:0016787 hydrolase activity MF
GO:0016798 hydrolase activity, acting on glycosyl bonds MF
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds MF
GO:0019104 DNA N-glycosylase activity MF
GO:0032131 alkylated DNA binding MF
GO:0032991 protein-containing complex CC
GO:0032993 protein-DNA complex CC
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035510 DNA dealkylation BP
GO:0043170 macromolecule metabolic process BP
GO:0043412 macromolecule modification BP
GO:0043733 DNA-3-methylbase glycosylase activity MF
GO:0043916 DNA-7-methylguanine glycosylase activity MF
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0045007 depurination BP
GO:0046483 heterocycle metabolic process BP
GO:0050896 response to stimulus BP
GO:0051716 cellular response to stimulus BP
GO:0052820 DNA-1,N6-ethenoadenine N-glycosylase activity MF
GO:0071704 organic substance metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
KEGG Term Name Description
map03410 Base excision repair Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.