Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
Potra2n7c15474
View in Genome Browser
Position
chr7:631108-647073 (-)
15965bp
Gene Type
gene
Gene Description (Protein Product)
DDB1- and CUL4-associated factor
26S proteasome non-ATPase regulatory subunit
Organism
Populus tremula
Also AS Potri.007G137300Potri.007G137200AT4G28450AT2G20580Potri.007G137300.v4.1Potri.007G137200.v4.1

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Potra2n7c16147 Lysosomal
Potra2n7c16147 26S proteasome non-atpase regulatory subunit
Potra2n7c16067 Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000151 ubiquitin ligase complex CC
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) BP
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005730 nucleolus CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006364 rRNA processing BP
GO:0006396 RNA processing BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009987 cellular process BP
GO:0010467 gene expression BP
GO:0016070 RNA metabolic process BP
GO:0016072 rRNA metabolic process BP
GO:0022613 ribonucleoprotein complex biogenesis BP
GO:0030490 maturation of SSU-rRNA BP
GO:0030684 preribosome CC
GO:0031461 cullin-RING ubiquitin ligase complex CC
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032040 small-subunit processome CC
GO:0032991 protein-containing complex CC
GO:0034470 ncRNA processing BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034660 ncRNA metabolic process BP
GO:0042254 ribosome biogenesis BP
GO:0042274 ribosomal small subunit biogenesis BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080008 Cul4-RING E3 ubiquitin ligase complex CC
GO:0090304 nucleic acid metabolic process BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1902494 catalytic complex CC
GO:1990234 transferase complex CC
GO:1990904 ribonucleoprotein complex CC
GO:0000502 proteasome complex CC
GO:0001101 response to acid chemical BP
GO:0002376 immune system process BP
GO:0003674 molecular_function MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0005838 proteasome regulatory particle CC
GO:0005886 plasma membrane CC
GO:0005911 cell-cell junction CC
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006950 response to stress BP
GO:0006952 defense response BP
GO:0006955 immune response BP
GO:0008540 proteasome regulatory particle, base subcomplex CC
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009506 plasmodesma CC
GO:0009719 response to endogenous stimulus BP
GO:0009725 response to hormone BP
GO:0009751 response to salicylic acid BP
GO:0010033 response to organic substance BP
GO:0010498 proteasomal protein catabolic process BP
GO:0014070 response to organic cyclic compound BP
GO:0016020 membrane CC
GO:0019538 protein metabolic process BP
GO:0019941 modification-dependent protein catabolic process BP
GO:0022624 proteasome accessory complex CC
GO:0030054 cell junction CC
GO:0030163 protein catabolic process BP
GO:0031597 cytosolic proteasome complex CC
GO:0032182 ubiquitin-like protein binding MF
GO:0034515 proteasome storage granule CC
GO:0042221 response to chemical BP
GO:0042493 response to xenobiotic stimulus BP
GO:0043130 ubiquitin binding MF
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process BP
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044444 obsolete cytoplasmic part CC
GO:0044445 obsolete cytosolic part CC
GO:0045087 innate immune response BP
GO:0046677 response to antibiotic BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0051726 regulation of cell cycle BP
GO:0055044 symplast CC
GO:0065007 biological regulation BP
GO:0071944 cell periphery CC
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901700 response to oxygen-containing compound BP
GO:1905368 peptidase complex CC
GO:1905369 endopeptidase complex CC
KEGG Term Name Description
map03050 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.