PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	Potra2n7c15501 View in Genome Browser
Position	chr7:851011-853147 (+) 2136bp
Gene Type	gene
Gene Description (Protein Product)	ribosome biogenesis protein U3 snoRNA binding
Organism	Populus tremula
Also AS	Potri.017G017700AT1G06720Potri.017G017700.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

Potra2n9c19650 Involved in the biogenesis of the 60S ribosomal subunit

Potra2n9c19650

Potra2n9c19967 Large subunit GTPase

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0000166	nucleotide binding	MF
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	BP
GO:0000469	cleavage involved in rRNA processing	BP
GO:0000478	endonucleolytic cleavage involved in rRNA processing	BP
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	BP
GO:0001882	nucleoside binding	MF
GO:0001883	purine nucleoside binding	MF
GO:0003674	molecular_function	MF
GO:0003676	nucleic acid binding	MF
GO:0003723	RNA binding	MF
GO:0003824	catalytic activity	MF
GO:0003924	GTPase activity	MF
GO:0005488	binding	MF
GO:0005525	GTP binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005730	nucleolus	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006364	rRNA processing	BP
GO:0006396	RNA processing	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009987	cellular process	BP
GO:0010467	gene expression	BP
GO:0016070	RNA metabolic process	BP
GO:0016072	rRNA metabolic process	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016787	hydrolase activity	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0017076	purine nucleotide binding	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0019001	guanyl nucleotide binding	MF
GO:0022613	ribonucleoprotein complex biogenesis	BP
GO:0030490	maturation of SSU-rRNA	BP
GO:0030515	snoRNA binding	MF
GO:0030684	preribosome	CC
GO:0030686	90S preribosome	CC
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0032549	ribonucleoside binding	MF
GO:0032550	purine ribonucleoside binding	MF
GO:0032553	ribonucleotide binding	MF
GO:0032555	purine ribonucleotide binding	MF
GO:0032561	guanyl ribonucleotide binding	MF
GO:0032991	protein-containing complex	CC
GO:0034470	ncRNA processing	BP
GO:0034511	U3 snoRNA binding	MF
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034660	ncRNA metabolic process	BP
GO:0035639	purine ribonucleoside triphosphate binding	MF
GO:0036094	small molecule binding	MF
GO:0042254	ribosome biogenesis	BP
GO:0042274	ribosomal small subunit biogenesis	BP
GO:0043167	ion binding	MF
GO:0043168	anion binding	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0044085	cellular component biogenesis	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0070013	intracellular organelle lumen	CC
GO:0071704	organic substance metabolic process	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090305	nucleic acid phosphodiester bond hydrolysis	BP
GO:0090501	RNA phosphodiester bond hydrolysis	BP
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	BP
GO:0097159	organic cyclic compound binding	MF
GO:0097367	carbohydrate derivative binding	MF
GO:1901265	nucleoside phosphate binding	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1990904	ribonucleoprotein complex	CC
GO:0001959	regulation of cytokine-mediated signaling pathway	BP
GO:0001960	negative regulation of cytokine-mediated signaling pathway	BP
GO:0002682	regulation of immune system process	BP
GO:0002683	negative regulation of immune system process	BP
GO:0006417	regulation of translation	BP
GO:0006508	proteolysis	BP
GO:0008233	peptidase activity	MF
GO:0008234	cysteine-type peptidase activity	MF
GO:0009605	response to external stimulus	BP
GO:0009607	response to biotic stimulus	BP
GO:0009889	regulation of biosynthetic process	BP
GO:0009892	negative regulation of metabolic process	BP
GO:0009893	positive regulation of metabolic process	BP
GO:0009894	regulation of catabolic process	BP
GO:0009896	positive regulation of catabolic process	BP
GO:0009966	regulation of signal transduction	BP
GO:0009968	negative regulation of signal transduction	BP
GO:0010468	regulation of gene expression	BP
GO:0010506	regulation of autophagy	BP
GO:0010508	positive regulation of autophagy	BP
GO:0010556	regulation of macromolecule biosynthetic process	BP
GO:0010605	negative regulation of macromolecule metabolic process	BP
GO:0010608	post-transcriptional regulation of gene expression	BP
GO:0010629	negative regulation of gene expression	BP
GO:0010646	regulation of cell communication	BP
GO:0010648	negative regulation of cell communication	BP
GO:0016032	viral process	BP
GO:0018995	host cellular component	CC
GO:0019048	modulation by virus of host process	BP
GO:0019049	mitigation of host antiviral defense response	BP
GO:0019054	modulation by virus of host cellular process	BP
GO:0019056	modulation by virus of host transcription	BP
GO:0019057	modulation by virus of host translation	BP
GO:0019058	viral life cycle	BP
GO:0019079	viral genome replication	BP
GO:0019219	regulation of nucleobase-containing compound metabolic process	BP
GO:0019222	regulation of metabolic process	BP
GO:0019538	protein metabolic process	BP
GO:0019783	ubiquitin-like protein peptidase activity	MF
GO:0019785	ISG15-specific peptidase activity	MF
GO:0020012	evasion of host immune response	BP
GO:0023051	regulation of signaling	BP
GO:0023057	negative regulation of signaling	BP
GO:0030430	host cell cytoplasm	CC
GO:0030682	mitigation of host defenses by symbiont	BP
GO:0030683	mitigation of host antiviral defense response	BP
GO:0031323	regulation of cellular metabolic process	BP
GO:0031325	positive regulation of cellular metabolic process	BP
GO:0031326	regulation of cellular biosynthetic process	BP
GO:0031329	regulation of cellular catabolic process	BP
GO:0031331	positive regulation of cellular catabolic process	BP
GO:0031347	regulation of defense response	BP
GO:0031348	negative regulation of defense response	BP
GO:0032268	regulation of protein metabolic process	BP
GO:0033643	host cell part	CC
GO:0033646	host intracellular part	CC
GO:0033647	host intracellular organelle	CC
GO:0033648	host intracellular membrane-bounded organelle	CC
GO:0034248	regulation of amide metabolic process	BP
GO:0035821	modulation of process of another organism	BP
GO:0039502	suppression by virus of host type I interferon-mediated signaling pathway	BP
GO:0039503	suppression by virus of host innate immune response	BP
GO:0039506	modulation by virus of host molecular function	BP
GO:0039507	suppression by virus of host molecular function	BP
GO:0039519	modulation by virus of host autophagy	BP
GO:0039520	induction by virus of host autophagy	BP
GO:0039579	suppression by virus of host ISG15-protein conjugation	BP
GO:0039604	suppression by virus of host translation	BP
GO:0039606	suppression by virus of host translation initiation	BP
GO:0039611	obsolete suppression by virus of host translation initiation factor activity	BP
GO:0039644	suppression by virus of host NF-kappaB cascade	BP
GO:0039648	modulation by virus of host protein ubiquitination	BP
GO:0039653	suppression by virus of host transcription	BP
GO:0039656	modulation by virus of host gene expression	BP
GO:0039657	suppression by virus of host gene expression	BP
GO:0039690	positive stranded viral RNA replication	BP
GO:0039694	viral RNA genome replication	BP
GO:0042025	host cell nucleus	CC
GO:0043207	response to external biotic stimulus	BP
GO:0043656	host intracellular region	CC
GO:0043657	host cell	CC
GO:0044003	modulation by symbiont of host process	BP
GO:0044068	modulation by symbiont of host cellular process	BP
GO:0044073	modulation by symbiont of host translation	BP
GO:0044092	negative regulation of molecular function	BP
GO:0044215	obsolete other organism	CC
GO:0044216	obsolete other organism cell	CC
GO:0044217	other organism part	CC
GO:0044359	modulation of molecular function in another organism	BP
GO:0044362	negative regulation of molecular function in another organism	BP
GO:0044403	biological process involved in symbiotic interaction	BP
GO:0044413	mitigation of host defenses by symbiont	BP
GO:0044414	suppression of host defenses by symbiont	BP
GO:0044415	mitigation of host defenses by symbiont	BP
GO:0044419	biological process involved in interspecies interaction between organisms	BP
GO:0044501	modulation of signal transduction in another organism	BP
GO:0045088	regulation of innate immune response	BP
GO:0045824	negative regulation of innate immune response	BP
GO:0048518	positive regulation of biological process	BP
GO:0048519	negative regulation of biological process	BP
GO:0048522	positive regulation of cellular process	BP
GO:0048523	negative regulation of cellular process	BP
GO:0048583	regulation of response to stimulus	BP
GO:0048585	negative regulation of response to stimulus	BP
GO:0050690	mitigation of host antiviral defense response	BP
GO:0050776	regulation of immune response	BP
GO:0050777	negative regulation of immune response	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0050896	response to stimulus	BP
GO:0051171	regulation of nitrogen compound metabolic process	BP
GO:0051246	regulation of protein metabolic process	BP
GO:0051252	regulation of RNA metabolic process	BP
GO:0051701	biological process involved in interaction with host	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051707	response to other organism	BP
GO:0051805	evasion of host immune response	BP
GO:0051807	mitigation of host defenses by symbiont	BP
GO:0051817	obsolete modulation of process of other organism involved in symbiotic interaction	BP
GO:0051832	mitigation of host defenses by symbiont	BP
GO:0051833	suppression of host defenses by symbiont	BP
GO:0051834	mitigation of host defenses by symbiont	BP
GO:0052026	modulation by symbiont of host transcription	BP
GO:0052027	modulation by symbiont of host signal transduction pathway	BP
GO:0052029	suppression by symbiont of host signal transduction pathway	BP
GO:0052031	modulation by symbiont of host defense response	BP
GO:0052037	suppression of host defenses by symbiont	BP
GO:0052055	modulation by symbiont of host molecular function	BP
GO:0052056	negative regulation by symbiont of host catalytic activity	BP
GO:0052167	modulation by symbiont of host innate immune response	BP
GO:0052170	suppression by symbiont of host innate immune response	BP
GO:0052173	response to defenses of other organism	BP
GO:0052200	response to host defenses	BP
GO:0052204	obsolete negative regulation of molecular function in other organism involved in symbiotic interaction	BP
GO:0052205	obsolete modulation of molecular function in other organism involved in symbiotic interaction	BP
GO:0052250	modulation by symbiont of host signal transduction pathway	BP
GO:0052255	modulation by symbiont of host defense response	BP
GO:0052261	suppression of host defenses by symbiont	BP
GO:0052306	modulation by symbiont of host innate immune response	BP
GO:0052309	suppression by symbiont of host innate immune response	BP
GO:0052312	obsolete modulation of transcription in other organism involved in symbiotic interaction	BP
GO:0052493	suppression by symbiont of host signal transduction pathway	BP
GO:0052552	modulation by symbiont of host immune response	BP
GO:0052553	modulation by symbiont of host immune response	BP
GO:0052561	suppression by symbiont of host immune response	BP
GO:0052562	suppression by symbiont of host immune response	BP
GO:0052564	response to host immune response	BP
GO:0052572	response to host immune response	BP
GO:0060255	regulation of macromolecule metabolic process	BP
GO:0060338	regulation of type I interferon-mediated signaling pathway	BP
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	BP
GO:0060759	regulation of response to cytokine stimulus	BP
GO:0060761	negative regulation of response to cytokine stimulus	BP
GO:0065007	biological regulation	BP
GO:0065009	regulation of molecular function	BP
GO:0070011	peptidase activity	MF
GO:0075109	modulation by symbiont of host receptor-mediated signal transduction	BP
GO:0075111	suppression by symbiont of host receptor-mediated signal transduction	BP
GO:0075112	modulation by symbiont of host transmembrane receptor-mediated signal transduction	BP
GO:0075114	suppression by symbiont of host transmembrane receptor-mediated signal transduction	BP
GO:0075136	response to host	BP
GO:0075528	modulation by virus of host immune response	BP
GO:0080090	regulation of primary metabolic process	BP
GO:0080134	regulation of response to stress	BP
GO:0140096	catalytic activity, acting on a protein	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:2000112	regulation of cellular macromolecule biosynthetic process	BP
GO:2001141	regulation of RNA biosynthetic process	BP

KEGG Term	Name	Description
map03008	Ribosome biogenesis in eukaryotes	Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage.