PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	Potra2n8c17786 View in Genome Browser
Position	chr8:8029847-8042459 (+) 12612bp
Gene Type	gene
Gene Description (Protein Product)	fructose-bisphosphate aldolase ATP-dependent RNA helicase
Organism	Populus tremula
Also AS	Potri.008G125900Potri.010G117800AT2G01140AT2G01130Potri.008G125900.v4.1Potri.010G117800.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

Potra2n9c19374 -

Potra2n9c19374 Belongs to the pyruvate kinase family

Potra2n8c18284 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004332	fructose-bisphosphate aldolase activity	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005739	mitochondrion	CC
GO:0005975	carbohydrate metabolic process	BP
GO:0005996	monosaccharide metabolic process	BP
GO:0006006	glucose metabolic process	BP
GO:0006082	organic acid metabolic process	BP
GO:0006090	pyruvate metabolic process	BP
GO:0006091	generation of precursor metabolites and energy	BP
GO:0006094	gluconeogenesis	BP
GO:0006096	glycolytic process	BP
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006163	purine nucleotide metabolic process	BP
GO:0006164	purine nucleotide biosynthetic process	BP
GO:0006165	nucleoside diphosphate phosphorylation	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006732	obsolete coenzyme metabolic process	BP
GO:0006733	obsolete oxidoreduction coenzyme metabolic process	BP
GO:0006753	nucleoside phosphate metabolic process	BP
GO:0006754	ATP biosynthetic process	BP
GO:0006757	ATP generation from ADP	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006979	response to oxidative stress	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009056	catabolic process	BP
GO:0009058	biosynthetic process	BP
GO:0009108	obsolete coenzyme biosynthetic process	BP
GO:0009117	nucleotide metabolic process	BP
GO:0009123	nucleoside monophosphate metabolic process	BP
GO:0009124	nucleoside monophosphate biosynthetic process	BP
GO:0009126	purine nucleoside monophosphate metabolic process	BP
GO:0009127	purine nucleoside monophosphate biosynthetic process	BP
GO:0009132	nucleoside diphosphate metabolic process	BP
GO:0009135	purine nucleoside diphosphate metabolic process	BP
GO:0009141	nucleoside triphosphate metabolic process	BP
GO:0009142	nucleoside triphosphate biosynthetic process	BP
GO:0009144	purine nucleoside triphosphate metabolic process	BP
GO:0009145	purine nucleoside triphosphate biosynthetic process	BP
GO:0009150	purine ribonucleotide metabolic process	BP
GO:0009152	purine ribonucleotide biosynthetic process	BP
GO:0009156	ribonucleoside monophosphate biosynthetic process	BP
GO:0009161	ribonucleoside monophosphate metabolic process	BP
GO:0009165	nucleotide biosynthetic process	BP
GO:0009166	nucleotide catabolic process	BP
GO:0009167	purine ribonucleoside monophosphate metabolic process	BP
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	BP
GO:0009179	purine ribonucleoside diphosphate metabolic process	BP
GO:0009185	ribonucleoside diphosphate metabolic process	BP
GO:0009199	ribonucleoside triphosphate metabolic process	BP
GO:0009201	ribonucleoside triphosphate biosynthetic process	BP
GO:0009205	purine ribonucleoside triphosphate metabolic process	BP
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	BP
GO:0009259	ribonucleotide metabolic process	BP
GO:0009260	ribonucleotide biosynthetic process	BP
GO:0009507	chloroplast	CC
GO:0009532	plastid stroma	CC
GO:0009534	chloroplast thylakoid	CC
GO:0009536	plastid	CC
GO:0009570	chloroplast stroma	CC
GO:0009579	thylakoid	CC
GO:0009987	cellular process	BP
GO:0010035	response to inorganic substance	BP
GO:0010038	response to metal ion	BP
GO:0010287	plastoglobule	CC
GO:0016051	carbohydrate biosynthetic process	BP
GO:0016052	carbohydrate catabolic process	BP
GO:0016053	organic acid biosynthetic process	BP
GO:0016310	phosphorylation	BP
GO:0016829	lyase activity	MF
GO:0016830	carbon-carbon lyase activity	MF
GO:0016832	aldehyde-lyase activity	MF
GO:0017144	xenobiotic metabolic process	BP
GO:0018130	heterocycle biosynthetic process	BP
GO:0019318	hexose metabolic process	BP
GO:0019319	hexose biosynthetic process	BP
GO:0019359	nicotinamide nucleotide biosynthetic process	BP
GO:0019362	pyridine nucleotide metabolic process	BP
GO:0019363	pyridine nucleotide biosynthetic process	BP
GO:0019438	aromatic compound biosynthetic process	BP
GO:0019439	aromatic compound catabolic process	BP
GO:0019637	organophosphate metabolic process	BP
GO:0019693	ribose phosphate metabolic process	BP
GO:0019752	carboxylic acid metabolic process	BP
GO:0031976	plastid thylakoid	CC
GO:0031984	organelle subcompartment	CC
GO:0032787	monocarboxylic acid metabolic process	BP
GO:0034404	nucleobase-containing small molecule biosynthetic process	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034654	nucleobase-containing compound biosynthetic process	BP
GO:0034655	nucleobase-containing compound catabolic process	BP
GO:0042221	response to chemical	BP
GO:0042866	pyruvate biosynthetic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043436	oxoacid metabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044270	cellular nitrogen compound catabolic process	BP
GO:0044271	cellular nitrogen compound biosynthetic process	BP
GO:0044281	small molecule metabolic process	BP
GO:0044283	small molecule biosynthetic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044434	obsolete chloroplast part	CC
GO:0044435	obsolete plastid part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0046031	ADP metabolic process	BP
GO:0046034	ATP metabolic process	BP
GO:0046364	monosaccharide biosynthetic process	BP
GO:0046390	ribose phosphate biosynthetic process	BP
GO:0046394	carboxylic acid biosynthetic process	BP
GO:0046434	organophosphate catabolic process	BP
GO:0046483	heterocycle metabolic process	BP
GO:0046496	nicotinamide nucleotide metabolic process	BP
GO:0046686	response to cadmium ion	BP
GO:0046700	heterocycle catabolic process	BP
GO:0046939	nucleotide phosphorylation	BP
GO:0050896	response to stimulus	BP
GO:0051186	obsolete cofactor metabolic process	BP
GO:0051188	obsolete cofactor biosynthetic process	BP
GO:0055086	nucleobase-containing small molecule metabolic process	BP
GO:0071704	organic substance metabolic process	BP
GO:0072330	monocarboxylic acid biosynthetic process	BP
GO:0072521	purine-containing compound metabolic process	BP
GO:0072522	purine-containing compound biosynthetic process	BP
GO:0072524	pyridine-containing compound metabolic process	BP
GO:0072525	pyridine-containing compound biosynthetic process	BP
GO:0090407	organophosphate biosynthetic process	BP
GO:1901135	carbohydrate derivative metabolic process	BP
GO:1901137	carbohydrate derivative biosynthetic process	BP
GO:1901292	nucleoside phosphate catabolic process	BP
GO:1901293	nucleoside phosphate biosynthetic process	BP
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901361	organic cyclic compound catabolic process	BP
GO:1901362	organic cyclic compound biosynthetic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901566	organonitrogen compound biosynthetic process	BP
GO:1901575	organic substance catabolic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:0000976	transcription cis-regulatory region binding	MF
GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	MF
GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	MF
GO:0000987	cis-regulatory region sequence-specific DNA binding	MF
GO:0001012	RNA polymerase II transcription regulatory region sequence-specific DNA binding	MF
GO:0001047	core promoter sequence-specific DNA binding	MF
GO:0001067	transcription regulatory region nucleic acid binding	MF
GO:0001503	ossification	BP
GO:0001817	regulation of cytokine production	BP
GO:0001819	positive regulation of cytokine production	BP
GO:0002151	G-quadruplex RNA binding	MF
GO:0002791	regulation of peptide secretion	BP
GO:0002793	positive regulation of peptide secretion	BP
GO:0003676	nucleic acid binding	MF
GO:0003677	DNA binding	MF
GO:0003690	double-stranded DNA binding	MF
GO:0003697	single-stranded DNA binding	MF
GO:0003723	RNA binding	MF
GO:0003724	RNA helicase activity	MF
GO:0003725	double-stranded RNA binding	MF
GO:0004004	RNA helicase activity	MF
GO:0004386	helicase activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005634	nucleus	CC
GO:0005829	cytosol	CC
GO:0006355	regulation of DNA-templated transcription	BP
GO:0006357	regulation of transcription by RNA polymerase II	BP
GO:0006396	RNA processing	BP
GO:0008026	helicase activity	MF
GO:0008094	ATP-dependent activity, acting on DNA	MF
GO:0008186	ATP-dependent activity, acting on RNA	MF
GO:0009605	response to external stimulus	BP
GO:0009607	response to biotic stimulus	BP
GO:0009615	response to virus	BP
GO:0009889	regulation of biosynthetic process	BP
GO:0009891	positive regulation of biosynthetic process	BP
GO:0009892	negative regulation of metabolic process	BP
GO:0009893	positive regulation of metabolic process	BP
GO:0009894	regulation of catabolic process	BP
GO:0009895	negative regulation of catabolic process	BP
GO:0010033	response to organic substance	BP
GO:0010467	gene expression	BP
GO:0010468	regulation of gene expression	BP
GO:0010501	RNA secondary structure unwinding	BP
GO:0010556	regulation of macromolecule biosynthetic process	BP
GO:0010557	positive regulation of macromolecule biosynthetic process	BP
GO:0010604	positive regulation of macromolecule metabolic process	BP
GO:0010605	negative regulation of macromolecule metabolic process	BP
GO:0010608	post-transcriptional regulation of gene expression	BP
GO:0010628	positive regulation of gene expression	BP
GO:0010638	positive regulation of organelle organization	BP
GO:0014070	response to organic cyclic compound	BP
GO:0016070	RNA metabolic process	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016787	hydrolase activity	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0016887	ATP hydrolysis activity	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0019219	regulation of nucleobase-containing compound metabolic process	BP
GO:0019222	regulation of metabolic process	BP
GO:0019899	enzyme binding	MF
GO:0031323	regulation of cellular metabolic process	BP
GO:0031324	negative regulation of cellular metabolic process	BP
GO:0031325	positive regulation of cellular metabolic process	BP
GO:0031326	regulation of cellular biosynthetic process	BP
GO:0031328	positive regulation of cellular biosynthetic process	BP
GO:0031329	regulation of cellular catabolic process	BP
GO:0031330	negative regulation of cellular catabolic process	BP
GO:0032204	regulation of telomere maintenance	BP
GO:0032206	positive regulation of telomere maintenance	BP
GO:0032479	regulation of type I interferon production	BP
GO:0032481	positive regulation of type I interferon production	BP
GO:0032501	multicellular organismal process	BP
GO:0032647	regulation of interferon-alpha production	BP
GO:0032727	positive regulation of interferon-alpha production	BP
GO:0032879	regulation of localization	BP
GO:0032880	regulation of protein localization	BP
GO:0033043	regulation of organelle organization	BP
GO:0033044	regulation of chromosome organization	BP
GO:0042623	ATP hydrolysis activity	MF
GO:0042826	histone deacetylase binding	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043207	response to external biotic stimulus	BP
GO:0043330	response to exogenous dsRNA	BP
GO:0043331	response to dsRNA	BP
GO:0043487	regulation of RNA stability	BP
GO:0043489	RNA stabilization	BP
GO:0043565	sequence-specific DNA binding	MF
GO:0044212	transcription cis-regulatory region binding	MF
GO:0045893	positive regulation of DNA-templated transcription	BP
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	BP
GO:0045935	positive regulation of nucleobase-containing compound metabolic process	BP
GO:0045944	positive regulation of transcription by RNA polymerase II	BP
GO:0048518	positive regulation of biological process	BP
GO:0048519	negative regulation of biological process	BP
GO:0048522	positive regulation of cellular process	BP
GO:0048523	negative regulation of cellular process	BP
GO:0050707	regulation of cytokine production	BP
GO:0050708	regulation of protein secretion	BP
GO:0050714	positive regulation of protein secretion	BP
GO:0050715	positive regulation of cytokine production	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0051046	regulation of secretion	BP
GO:0051047	positive regulation of secretion	BP
GO:0051049	regulation of transport	BP
GO:0051050	positive regulation of transport	BP
GO:0051052	regulation of DNA metabolic process	BP
GO:0051054	positive regulation of DNA metabolic process	BP
GO:0051128	regulation of cellular component organization	BP
GO:0051130	positive regulation of cellular component organization	BP
GO:0051171	regulation of nitrogen compound metabolic process	BP
GO:0051172	negative regulation of nitrogen compound metabolic process	BP
GO:0051173	positive regulation of nitrogen compound metabolic process	BP
GO:0051222	positive regulation of protein transport	BP
GO:0051223	regulation of protein transport	BP
GO:0051239	regulation of multicellular organismal process	BP
GO:0051240	positive regulation of multicellular organismal process	BP
GO:0051252	regulation of RNA metabolic process	BP
GO:0051253	negative regulation of RNA metabolic process	BP
GO:0051254	positive regulation of RNA metabolic process	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051707	response to other organism	BP
GO:0051880	G-quadruplex DNA binding	MF
GO:0060255	regulation of macromolecule metabolic process	BP
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0070034	telomerase RNA binding	MF
GO:0070035	obsolete purine NTP-dependent helicase activity	MF
GO:0070201	regulation of establishment of protein localization	BP
GO:0080090	regulation of primary metabolic process	BP
GO:0090087	regulation of peptide transport	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090669	telomerase RNA stabilization	BP
GO:0097159	organic cyclic compound binding	MF
GO:0140098	catalytic activity, acting on RNA	MF
GO:1901363	heterocyclic compound binding	MF
GO:1901698	response to nitrogen compound	BP
GO:1902369	negative regulation of RNA catabolic process	BP
GO:1902680	positive regulation of RNA biosynthetic process	BP
GO:1902739	regulation of interferon-alpha production	BP
GO:1902741	positive regulation of interferon-alpha production	BP
GO:1903506	regulation of nucleic acid-templated transcription	BP
GO:1903508	positive regulation of nucleic acid-templated transcription	BP
GO:1903530	regulation of secretion by cell	BP
GO:1903532	positive regulation of secretion by cell	BP
GO:1904951	positive regulation of establishment of protein localization	BP
GO:1990837	sequence-specific double-stranded DNA binding	MF
GO:2000112	regulation of cellular macromolecule biosynthetic process	BP
GO:2001141	regulation of RNA biosynthetic process	BP
GO:2001252	positive regulation of chromosome organization	BP

KEGG Term	Name	Description
map03018	RNA degradation	The correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay exist and both pathways are initiated by poly(A) shortening of the mRNA. In the 5' to 3' pathway, this is followed by decapping which then permits the 5' to 3' exonucleolytic degradation of transcripts. In the 3' to 5' pathway, the exosome, a large multisubunit complex, plays a key role. The exosome exists in archaeal cells, too. In bacteria, endoribonuclease E, a key enzyme involved in RNA decay and processing, organizes a protein complex called degradosome. RNase E or R interacts with the phosphate-dependent exoribonuclease polynucleotide phosphorylase, DEAD-box helicases, and additional factors in the RNA-degrading complex.
map01110	Biosynthesis of secondary metabolites	-
map01100	Metabolic pathways	-
map00710	Carbon fixation in photosynthetic organisms	-
map00051	Fructose and mannose metabolism	-
map00030	Pentose phosphate pathway	The pentose phosphate pathway is a process of glucose turnover that produces NADPH as reducing equivalents and pentoses as essential parts of nucleotides. There are two different phases in the pathway. One is irreversible oxidative phase in which glucose-6P is converted to ribulose-5P by oxidative decarboxylation, and NADPH is generated [MD:M00006]. The other is reversible non-oxidative phase in which phosphorylated sugars are interconverted to generate xylulose-5P, ribulose-5P, and ribose-5P [MD:M00007]. Phosphoribosyl pyrophosphate (PRPP) formed from ribose-5P [MD:M00005] is an activated compound used in the biosynthesis of histidine and purine/pyrimidine nucleotides. This pathway map also shows the Entner-Doudoroff pathway where 6-P-gluconate is dehydrated and then cleaved into pyruvate and glyceraldehyde-3P [MD:M00008].
map00010	Glycolysis / Gluconeogenesis	Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which often corresponds to operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].