Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000166 | nucleotide binding | MF |
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004148 | dihydrolipoyl dehydrogenase activity | MF |
| GO:0005488 | binding | MF |
| GO:0005507 | copper ion binding | MF |
| GO:0005524 | ATP binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005576 | extracellular region | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005739 | mitochondrion | CC |
| GO:0005740 | mitochondrial envelope | CC |
| GO:0005743 | mitochondrial inner membrane | CC |
| GO:0005746 | mitochondrial respirasome | CC |
| GO:0005747 | mitochondrial respiratory chain complex I | CC |
| GO:0005759 | mitochondrial matrix | CC |
| GO:0008144 | obsolete drug binding | MF |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0008270 | zinc ion binding | MF |
| GO:0009507 | chloroplast | CC |
| GO:0009536 | plastid | CC |
| GO:0010035 | response to inorganic substance | BP |
| GO:0010038 | response to metal ion | BP |
| GO:0016020 | membrane | CC |
| GO:0016491 | oxidoreductase activity | MF |
| GO:0016651 | oxidoreductase activity, acting on NAD(P)H | MF |
| GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors | MF |
| GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | MF |
| GO:0017076 | purine nucleotide binding | MF |
| GO:0019866 | organelle inner membrane | CC |
| GO:0030554 | adenyl nucleotide binding | MF |
| GO:0030964 | NADH dehydrogenase complex | CC |
| GO:0031090 | organelle membrane | CC |
| GO:0031966 | mitochondrial membrane | CC |
| GO:0031967 | organelle envelope | CC |
| GO:0031974 | membrane-enclosed lumen | CC |
| GO:0031975 | envelope | CC |
| GO:0032553 | ribonucleotide binding | MF |
| GO:0032555 | purine ribonucleotide binding | MF |
| GO:0032559 | adenyl ribonucleotide binding | MF |
| GO:0032991 | protein-containing complex | CC |
| GO:0035639 | purine ribonucleoside triphosphate binding | MF |
| GO:0036094 | small molecule binding | MF |
| GO:0042221 | response to chemical | BP |
| GO:0043167 | ion binding | MF |
| GO:0043168 | anion binding | MF |
| GO:0043169 | cation binding | MF |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043233 | organelle lumen | CC |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044425 | obsolete membrane part | CC |
| GO:0044429 | obsolete mitochondrial part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044455 | obsolete mitochondrial membrane part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0045271 | respiratory chain complex I | CC |
| GO:0046686 | response to cadmium ion | BP |
| GO:0046872 | metal ion binding | MF |
| GO:0046914 | transition metal ion binding | MF |
| GO:0048046 | apoplast | CC |
| GO:0050896 | response to stimulus | BP |
| GO:0050897 | cobalt ion binding | MF |
| GO:0055114 | obsolete oxidation-reduction process | BP |
| GO:0070013 | intracellular organelle lumen | CC |
| GO:0070469 | respirasome | CC |
| GO:0097159 | organic cyclic compound binding | MF |
| GO:0097367 | carbohydrate derivative binding | MF |
| GO:0098796 | membrane protein complex | CC |
| GO:0098798 | mitochondrial protein-containing complex | CC |
| GO:0098800 | inner mitochondrial membrane protein complex | CC |
| GO:0098803 | respiratory chain complex | CC |
| GO:1901265 | nucleoside phosphate binding | MF |
| GO:1901363 | heterocyclic compound binding | MF |
| GO:1902494 | catalytic complex | CC |
| GO:1990204 | oxidoreductase complex | CC |
| KEGG Term | Name | Description |
|---|---|---|
| map01110 | Biosynthesis of secondary metabolites | - |
| map01100 | Metabolic pathways | - |
| map00640 | Propanoate metabolism | - |
| map00630 | Glyoxylate and dicarboxylate metabolism | - |
| map00620 | Pyruvate metabolism | - |
| map00380 | Tryptophan metabolism | - |
| map00310 | Lysine degradation | - |
| map00280 | Valine, leucine and isoleucine degradation | - |
| map00260 | Glycine, serine and threonine metabolism | Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, threonine is derived from aspartate [MD:M00018]. |
| map00020 | Citrate cycle (TCA cycle) | The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011]. |
| map00010 | Glycolysis / Gluconeogenesis | Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which often corresponds to operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003]. |