Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0006259 | DNA metabolic process | BP |
| GO:0006281 | DNA repair | BP |
| GO:0006725 | cellular aromatic compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0006950 | response to stress | BP |
| GO:0006974 | cellular response to DNA damage stimulus | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009266 | response to temperature stimulus | BP |
| GO:0009314 | response to radiation | BP |
| GO:0009408 | response to heat | BP |
| GO:0009411 | response to UV | BP |
| GO:0009416 | response to light stimulus | BP |
| GO:0009628 | response to abiotic stimulus | BP |
| GO:0009987 | cellular process | BP |
| GO:0033554 | cellular response to stress | BP |
| GO:0034641 | cellular nitrogen compound metabolic process | BP |
| GO:0043170 | macromolecule metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044260 | cellular macromolecule metabolic process | BP |
| GO:0046483 | heterocycle metabolic process | BP |
| GO:0050896 | response to stimulus | BP |
| GO:0051716 | cellular response to stimulus | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0090304 | nucleic acid metabolic process | BP |
| GO:1901360 | organic cyclic compound metabolic process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map03420 | Nucleotide excision repair | Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar. |
| map03022 | Basal transcription factors | - |

