Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0006082 | organic acid metabolic process | BP |
| GO:0006091 | generation of precursor metabolites and energy | BP |
| GO:0006099 | tricarboxylic acid cycle | BP |
| GO:0006101 | citrate metabolic process | BP |
| GO:0006107 | oxaloacetate metabolic process | BP |
| GO:0006108 | malate metabolic process | BP |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0006725 | cellular aromatic compound metabolic process | BP |
| GO:0006732 | obsolete coenzyme metabolic process | BP |
| GO:0006733 | obsolete oxidoreduction coenzyme metabolic process | BP |
| GO:0006734 | NADH metabolic process | BP |
| GO:0006753 | nucleoside phosphate metabolic process | BP |
| GO:0006793 | phosphorus metabolic process | BP |
| GO:0006796 | phosphate-containing compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009060 | aerobic respiration | BP |
| GO:0009117 | nucleotide metabolic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0015980 | energy derivation by oxidation of organic compounds | BP |
| GO:0016020 | membrane | CC |
| GO:0016491 | oxidoreductase activity | MF |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | MF |
| GO:0016615 | malate dehydrogenase activity | MF |
| GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | MF |
| GO:0016999 | antibiotic metabolic process | BP |
| GO:0017144 | xenobiotic metabolic process | BP |
| GO:0019362 | pyridine nucleotide metabolic process | BP |
| GO:0019637 | organophosphate metabolic process | BP |
| GO:0019674 | NAD metabolic process | BP |
| GO:0019752 | carboxylic acid metabolic process | BP |
| GO:0030060 | L-malate dehydrogenase activity | MF |
| GO:0034641 | cellular nitrogen compound metabolic process | BP |
| GO:0043436 | oxoacid metabolic process | BP |
| GO:0043648 | dicarboxylic acid metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044281 | small molecule metabolic process | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0045333 | cellular respiration | BP |
| GO:0046483 | heterocycle metabolic process | BP |
| GO:0046496 | nicotinamide nucleotide metabolic process | BP |
| GO:0051186 | obsolete cofactor metabolic process | BP |
| GO:0055086 | nucleobase-containing small molecule metabolic process | BP |
| GO:0055114 | obsolete oxidation-reduction process | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0072350 | tricarboxylic acid metabolic process | BP |
| GO:0072524 | pyridine-containing compound metabolic process | BP |
| GO:1901360 | organic cyclic compound metabolic process | BP |
| GO:1901564 | organonitrogen compound metabolic process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map01110 | Biosynthesis of secondary metabolites | - |
| map01100 | Metabolic pathways | - |
| map00710 | Carbon fixation in photosynthetic organisms | - |
| map00630 | Glyoxylate and dicarboxylate metabolism | - |
| map00620 | Pyruvate metabolism | - |
| map00270 | Cysteine and methionine metabolism | Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034]. |
| map00020 | Citrate cycle (TCA cycle) | The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011]. |