Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000785 | chromatin | CC |
| GO:0003674 | molecular_function | MF |
| GO:0003682 | chromatin binding | MF |
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
| GO:0005488 | binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005634 | nucleus | CC |
| GO:0005694 | chromosome | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005829 | cytosol | CC |
| GO:0008150 | biological_process | BP |
| GO:0009314 | response to radiation | BP |
| GO:0009411 | response to UV | BP |
| GO:0009416 | response to light stimulus | BP |
| GO:0009605 | response to external stimulus | BP |
| GO:0009628 | response to abiotic stimulus | BP |
| GO:0009649 | entrainment of circadian clock | BP |
| GO:0010224 | response to UV-B | BP |
| GO:0019899 | enzyme binding | MF |
| GO:0042752 | regulation of circadian rhythm | BP |
| GO:0042802 | identical protein binding | MF |
| GO:0042803 | protein homodimerization activity | MF |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043228 | non-membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043232 | intracellular non-membrane-bounded organelle | CC |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044427 | obsolete chromosomal part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0046983 | protein dimerization activity | MF |
| GO:0050789 | regulation of biological process | BP |
| GO:0050896 | response to stimulus | BP |
| GO:0051020 | GTPase binding | MF |
| GO:0065007 | biological regulation | BP |
| GO:0065009 | regulation of molecular function | BP |
| GO:0098772 | molecular function regulator activity | MF |
| KEGG Term | Name | Description |
|---|---|---|
| map04120 | Ubiquitin mediated proteolysis | Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates. |