Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
gene-GBA52_023034
View in Genome Browser
Position
CM035472.1:6003945-6006286 (-)
2341bp
Gene Type
gene
Gene Description (Protein Product)
"Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search
Organism
Prunus armeniaca
Also AS MD15G1224500AT5G20850PRUPE_7G190800

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-GBA52_027300 DNA repair and recombination protein
gene-GBA52_025544 Belongs to the AAA ATPase family
gene-GBA52_024834 Crossover junction endonuclease

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000150 DNA strand exchange activity MF
GO:0000217 DNA secondary structure binding MF
GO:0000228 nuclear chromosome CC
GO:0000280 nuclear division BP
GO:0000400 four-way junction DNA binding MF
GO:0000724 double-strand break repair via homologous recombination BP
GO:0000725 recombinational repair BP
GO:0000730 DNA recombinase assembly BP
GO:0000793 condensed chromosome CC
GO:0000794 condensed nuclear chromosome CC
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003690 double-stranded DNA binding MF
GO:0003697 single-stranded DNA binding MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005694 chromosome CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006310 DNA recombination BP
GO:0006312 mitotic recombination BP
GO:0006355 regulation of DNA-templated transcription BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0007127 meiosis I BP
GO:0007131 reciprocal meiotic recombination BP
GO:0008094 ATP-dependent activity, acting on DNA MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009314 response to radiation BP
GO:0009628 response to abiotic stimulus BP
GO:0009889 regulation of biosynthetic process BP
GO:0009987 cellular process BP
GO:0010212 response to ionizing radiation BP
GO:0010332 response to gamma radiation BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0016043 cellular component organization BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0022607 cellular component assembly BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0033554 cellular response to stress BP
GO:0034622 protein-containing complex assembly BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035825 homologous recombination BP
GO:0042148 strand invasion BP
GO:0042623 ATP hydrolysis activity MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043933 protein-containing complex organization BP
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045003 double-strand break repair via synthesis-dependent strand annealing BP
GO:0046483 heterocycle metabolic process BP
GO:0048285 organelle fission BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051276 chromosome organization BP
GO:0051321 meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0061982 meiosis I cell cycle process BP
GO:0065003 protein-containing complex assembly BP
GO:0065004 protein-DNA complex assembly BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0070192 chromosome organization involved in meiotic cell cycle BP
GO:0071704 organic substance metabolic process BP
GO:0071824 protein-DNA complex subunit organization BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080090 regulation of primary metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090735 DNA repair complex assembly BP
GO:0097159 organic cyclic compound binding MF
GO:0140013 meiotic nuclear division BP
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1903046 meiotic cell cycle process BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2001141 regulation of RNA biosynthetic process BP
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.