Basic Information
Gene ID
gene-GBA52_027939
Position
CM035470.1:20467913-20471945 (+)
4032bp
Gene Type
gene
Gene Description (Protein Product)
Fumarate hydratase 1
Organism
Also AS MD00G1140200AT2G47510PRUPE_8G265300

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-GBA52_028720 Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked
gene-GBA52_028838 heme protein
gene-GBA52_029209 Belongs to the mitochondrial carrier (TC 2.A.29) family

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0003006 developmental process involved in reproduction BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004333 fumarate hydratase activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0005829 cytosol CC
GO:0006082 organic acid metabolic process BP
GO:0006091 generation of precursor metabolites and energy BP
GO:0006099 tricarboxylic acid cycle BP
GO:0006101 citrate metabolic process BP
GO:0006106 fumarate metabolic process BP
GO:0006108 malate metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006970 response to osmotic stress BP
GO:0006979 response to oxidative stress BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009060 aerobic respiration BP
GO:0009266 response to temperature stimulus BP
GO:0009409 response to cold BP
GO:0009628 response to abiotic stimulus BP
GO:0009631 cold acclimation BP
GO:0009651 response to salt stress BP
GO:0009856 pollination BP
GO:0009987 cellular process BP
GO:0010109 regulation of photosynthesis BP
GO:0015980 energy derivation by oxidation of organic compounds BP
GO:0016829 lyase activity MF
GO:0016835 carbon-oxygen lyase activity MF
GO:0016836 hydro-lyase activity MF
GO:0016999 antibiotic metabolic process BP
GO:0017144 xenobiotic metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019752 carboxylic acid metabolic process BP
GO:0022414 reproductive process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0032501 multicellular organismal process BP
GO:0032502 developmental process BP
GO:0042126 nitrate metabolic process BP
GO:0042128 nitrate assimilation BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043436 oxoacid metabolic process BP
GO:0043648 dicarboxylic acid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044281 small molecule metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044464 obsolete cell part CC
GO:0044706 multi-multicellular organism process BP
GO:0045333 cellular respiration BP
GO:0048856 anatomical structure development BP
GO:0048868 pollen tube development BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051704 obsolete multi-organism process BP
GO:0055114 obsolete oxidation-reduction process BP
GO:0065007 biological regulation BP
GO:0071704 organic substance metabolic process BP
GO:0071941 nitrogen cycle metabolic process BP
GO:0072350 tricarboxylic acid metabolic process BP
GO:2001057 reactive nitrogen species metabolic process BP
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00620 Pyruvate metabolism -
map00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].