PPGR - Gene Detail

Basic Information

Gene ID	gene-GBA52_028858 View in Genome Browser
Position	JADDKH010000030.1:74428-74914 (-) 486bp
Gene Type	gene
Gene Description (Protein Product)	poly ADP-ribose polymerase
Organism	Prunus armeniaca
Also AS	MD03G1289600AT4G02390PRUPE_8G262600

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-GBA52_028980 Cell cycle checkpoint protein

gene-GBA52_028948 Ganglioside-induced differentiation-associated protein

gene-GBA52_029100 SWI SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000726	obsolete non-recombinational repair	BP
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0003909	DNA ligase activity	MF
GO:0003910	DNA ligase (ATP) activity	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005737	cytoplasm	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006260	DNA replication	BP
GO:0006261	DNA-templated DNA replication	BP
GO:0006266	DNA ligation	BP
GO:0006271	DNA strand elongation involved in DNA replication	BP
GO:0006273	lagging strand elongation	BP
GO:0006281	DNA repair	BP
GO:0006302	double-strand break repair	BP
GO:0006303	double-strand break repair via nonhomologous end joining	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009058	biosynthetic process	BP
GO:0009059	macromolecule biosynthetic process	BP
GO:0009987	cellular process	BP
GO:0016070	RNA metabolic process	BP
GO:0016874	ligase activity	MF
GO:0016886	ligase activity, forming phosphoric ester bonds	MF
GO:0022616	DNA strand elongation	BP
GO:0033554	cellular response to stress	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034645	cellular macromolecule biosynthetic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0050896	response to stimulus	BP
GO:0051103	DNA ligation involved in DNA repair	BP
GO:0051716	cellular response to stimulus	BP
GO:0071704	organic substance metabolic process	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0140097	catalytic activity, acting on DNA	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901576	organic substance biosynthetic process	BP

KEGG Term	Name	Description
map03410	Base excision repair	Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.