PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	Prupe.3G128000.v2.1.g View in Genome Browser
Position	Pp03:12715004-12717448 (-) 2444bp
Gene Type	gene
Gene Description (Protein Product)	proteasome assembly
Organism	Prunus persica
Also AS	AT1G29150PRUPE_3G128000

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	Prupe.5G038400.v2.1.g 26S proteasome non-ATPase regulatory subunit Prupe.5G147900.v2.1.g 26S proteasome non-ATPase regulatory subunit Prupe.8G090700.v2.1.g Belongs to the AAA ATPase family
Regulatory gene	Prupe.1G068400.v2.1.g Homeobox-leucine zipper protein Prupe.1G267300.v2.1.g Homeobox-leucine zipper protein Prupe.1G271400.v2.1.g Homeobox-leucine zipper protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0000502	proteasome complex	CC
GO:0001775	cell activation	BP
GO:0002252	immune effector process	BP
GO:0002263	cell activation involved in immune response	BP
GO:0002274	myeloid leukocyte activation	BP
GO:0002275	myeloid cell activation involved in immune response	BP
GO:0002283	neutrophil activation involved in immune response	BP
GO:0002366	leukocyte activation involved in immune response	BP
GO:0002376	immune system process	BP
GO:0002443	leukocyte mediated immunity	BP
GO:0002444	myeloid leukocyte mediated immunity	BP
GO:0002446	neutrophil mediated immunity	BP
GO:0003674	molecular_function	MF
GO:0005198	structural molecule activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005576	extracellular region	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0005838	proteasome regulatory particle	CC
GO:0006464	protein modification process	BP
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006810	transport	BP
GO:0006887	exocytosis	BP
GO:0006950	response to stress	BP
GO:0006955	immune response	BP
GO:0006970	response to osmotic stress	BP
GO:0006972	hyperosmotic response	BP
GO:0007088	regulation of mitotic nuclear division	BP
GO:0007275	multicellular organism development	BP
GO:0007346	regulation of mitotic cell cycle	BP
GO:0007568	aging	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008340	determination of adult lifespan	BP
GO:0008541	proteasome regulatory particle, lid subcomplex	CC
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009896	positive regulation of catabolic process	BP
GO:0009987	cellular process	BP
GO:0010259	multicellular organism aging	BP
GO:0010498	proteasomal protein catabolic process	BP
GO:0010564	regulation of cell cycle process	BP
GO:0010638	positive regulation of organelle organization	BP
GO:0010965	regulation of mitotic sister chromatid separation	BP
GO:0012505	endomembrane system	CC
GO:0016043	cellular component organization	BP
GO:0016192	vesicle-mediated transport	BP
GO:0016579	protein deubiquitination	BP
GO:0019538	protein metabolic process	BP
GO:0019941	modification-dependent protein catabolic process	BP
GO:0022607	cellular component assembly	BP
GO:0022624	proteasome accessory complex	CC
GO:0030071	regulation of mitotic metaphase/anaphase transition	BP
GO:0030141	secretory granule	CC
GO:0030154	cell differentiation	BP
GO:0030163	protein catabolic process	BP
GO:0031331	positive regulation of cellular catabolic process	BP
GO:0031410	cytoplasmic vesicle	CC
GO:0031597	cytosolic proteasome complex	CC
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0031982	vesicle	CC
GO:0031983	vesicle lumen	CC
GO:0032270	positive regulation of protein metabolic process	BP
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	BP
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0032940	secretion by cell	BP
GO:0032991	protein-containing complex	CC
GO:0033043	regulation of organelle organization	BP
GO:0033044	regulation of chromosome organization	BP
GO:0033045	regulation of sister chromatid segregation	BP
GO:0033047	regulation of mitotic sister chromatid segregation	BP
GO:0034515	proteasome storage granule	CC
GO:0034622	protein-containing complex assembly	BP
GO:0034774	secretory granule lumen	CC
GO:0036211	protein modification process	BP
GO:0036230	granulocyte activation	BP
GO:0042119	neutrophil activation	BP
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043248	proteasome assembly	BP
GO:0043299	leukocyte degranulation	BP
GO:0043312	neutrophil degranulation	BP
GO:0043412	macromolecule modification	BP
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0043687	post-translational protein modification	BP
GO:0043933	protein-containing complex organization	BP
GO:0044085	cellular component biogenesis	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044433	obsolete cytoplasmic vesicle part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044445	obsolete cytosolic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0045055	regulated exocytosis	BP
GO:0045321	leukocyte activation	BP
GO:0045732	positive regulation of protein catabolic process	BP
GO:0045787	positive regulation of cell cycle	BP
GO:0045840	positive regulation of mitotic nuclear division	BP
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	BP
GO:0045862	positive regulation of proteolysis	BP
GO:0045931	positive regulation of mitotic cell cycle	BP
GO:0046903	secretion	BP
GO:0048518	positive regulation of biological process	BP
GO:0048522	positive regulation of cellular process	BP
GO:0048856	anatomical structure development	BP
GO:0048863	stem cell differentiation	BP
GO:0048869	cellular developmental process	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0050896	response to stimulus	BP
GO:0051128	regulation of cellular component organization	BP
GO:0051130	positive regulation of cellular component organization	BP
GO:0051179	localization	BP
GO:0051234	establishment of localization	BP
GO:0051247	positive regulation of protein metabolic process	BP
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0051726	regulation of cell cycle	BP
GO:0051781	positive regulation of cell division	BP
GO:0051783	regulation of nuclear division	BP
GO:0051785	positive regulation of nuclear division	BP
GO:0051983	regulation of chromosome segregation	BP
GO:0051984	positive regulation of chromosome segregation	BP
GO:0060205	cytoplasmic vesicle lumen	CC
GO:0062033	positive regulation of mitotic sister chromatid segregation	BP
GO:0065003	protein-containing complex assembly	BP
GO:0065007	biological regulation	BP
GO:0070013	intracellular organelle lumen	CC
GO:0070646	protein modification by small protein removal	BP
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0071704	organic substance metabolic process	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0090068	positive regulation of cell cycle process	BP
GO:0097708	intracellular vesicle	CC
GO:0099503	secretory vesicle	CC
GO:0101002	ficolin-1-rich granule	CC
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901575	organic substance catabolic process	BP
GO:1901800	positive regulation of proteasomal protein catabolic process	BP
GO:1901970	positive regulation of mitotic sister chromatid separation	BP
GO:1901987	regulation of cell cycle phase transition	BP
GO:1901989	positive regulation of cell cycle phase transition	BP
GO:1901990	regulation of mitotic cell cycle phase transition	BP
GO:1901992	positive regulation of mitotic cell cycle phase transition	BP
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	BP
GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	BP
GO:1902494	catalytic complex	CC
GO:1903052	positive regulation of proteolysis involved in protein catabolic process	BP
GO:1903364	positive regulation of protein catabolic process	BP
GO:1904813	ficolin-1-rich granule lumen	CC
GO:1905368	peptidase complex	CC
GO:1905369	endopeptidase complex	CC
GO:1905818	regulation of chromosome separation	BP
GO:1905820	positive regulation of chromosome separation	BP
GO:2001252	positive regulation of chromosome organization	BP

KEGG Term	Name	Description
map03050	Proteasome	The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.