PPGR - Gene Detail

Basic Information

Gene ID	gene-DKX38_009991 View in Genome Browser
Position	CM018577.1:12650181-12652145 (+) 1964bp
Gene Type	gene
Gene Description (Protein Product)	Muniscin C-terminal mu homology domain
Organism	Salix brachista
Also AS	AT5G57460

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-DKX38_014702 Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome

gene-DKX38_025293 TPLATE-like

gene-DKX38_028742 SH3 domain-containing protein

Regulatory gene

gene-DKX38_000126 AP2-like ethylene-responsive transcription factor

gene-DKX38_000422 transcription factor

gene-DKX38_000614 Dof zinc finger protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

KEGG Term	Name	Description
map03440	Homologous recombination	Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.