Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-IMY05_016G0130600
View in Genome Browser
Position
CM029814.1:10539210-10543796 (+)
4586bp
Gene Type
gene
Gene Description (Protein Product)
DNA repair endonuclease
Organism
Salix suchowensis
Also AS AT5G41150

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_018G0050200 Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses
gene-IMY05_C3439000100 Belongs to the helicase family
gene-IMY05_C0883001300 Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000014 single-stranded DNA endodeoxyribonuclease activity MF
GO:0000109 nucleotide-excision repair complex CC
GO:0000110 nucleotide-excision repair factor 1 complex CC
GO:0000280 nuclear division BP
GO:0000712 resolution of meiotic recombination intermediates BP
GO:0000724 double-strand break repair via homologous recombination BP
GO:0000725 recombinational repair BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003684 damaged DNA binding MF
GO:0003697 single-stranded DNA binding MF
GO:0003824 catalytic activity MF
GO:0004518 nuclease activity MF
GO:0004519 endonuclease activity MF
GO:0004520 DNA endonuclease activity MF
GO:0004536 deoxyribonuclease activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006289 nucleotide-excision repair BP
GO:0006296 obsolete nucleotide-excision repair, DNA incision, 5'-to lesion BP
GO:0006302 double-strand break repair BP
GO:0006310 DNA recombination BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006979 response to oxidative stress BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0007059 chromosome segregation BP
GO:0007127 meiosis I BP
GO:0007131 reciprocal meiotic recombination BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009314 response to radiation BP
GO:0009628 response to abiotic stimulus BP
GO:0009987 cellular process BP
GO:0016043 cellular component organization BP
GO:0016787 hydrolase activity MF
GO:0016788 hydrolase activity, acting on ester bonds MF
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0033683 obsolete nucleotide-excision repair, DNA incision BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035825 homologous recombination BP
GO:0036297 interstrand cross-link repair BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045132 meiotic chromosome segregation BP
GO:0046483 heterocycle metabolic process BP
GO:0048285 organelle fission BP
GO:0050896 response to stimulus BP
GO:0051304 chromosome separation BP
GO:0051307 meiotic chromosome separation BP
GO:0051321 meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0061982 meiosis I cell cycle process BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0097159 organic cyclic compound binding MF
GO:0098813 nuclear chromosome segregation BP
GO:0140013 meiotic nuclear division BP
GO:0140097 catalytic activity, acting on DNA MF
GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1903046 meiotic cell cycle process BP
GO:1990391 DNA repair complex CC
KEGG Term Name Description
map03420 Nucleotide excision repair Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar.