Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-IMY05_016G0140300
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Position
CM029814.1:11760504-11764854 (+)
4350bp
Gene Type
gene
Gene Description (Protein Product)
"The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg
Organism
Salix suchowensis
Also AS AT3G14290

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C5091000300 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH
gene-IMY05_C4728000100 Belongs to the AAA ATPase family
gene-IMY05_017G0056400 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000502 proteasome complex CC
GO:0003674 molecular_function MF
GO:0003735 structural constituent of ribosome MF
GO:0003824 catalytic activity MF
GO:0004518 nuclease activity MF
GO:0004540 ribonuclease activity MF
GO:0005198 structural molecule activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005773 vacuole CC
GO:0005774 vacuolar membrane CC
GO:0005829 cytosol CC
GO:0005839 proteasome core complex CC
GO:0005840 ribosome CC
GO:0005844 polysome CC
GO:0005886 plasma membrane CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009987 cellular process BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0016020 membrane CC
GO:0016070 RNA metabolic process BP
GO:0016787 hydrolase activity MF
GO:0016788 hydrolase activity, acting on ester bonds MF
GO:0019773 proteasome core complex, alpha-subunit complex CC
GO:0022626 cytosolic ribosome CC
GO:0031090 organelle membrane CC
GO:0032991 protein-containing complex CC
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0042221 response to chemical BP
GO:0042788 polysomal ribosome CC
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044437 obsolete vacuolar part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044445 obsolete cytosolic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0046686 response to cadmium ion BP
GO:0050896 response to stimulus BP
GO:0071704 organic substance metabolic process BP
GO:0071944 cell periphery CC
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0090501 RNA phosphodiester bond hydrolysis BP
GO:0098588 bounding membrane of organelle CC
GO:0098805 membrane CC
GO:0140098 catalytic activity, acting on RNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1902494 catalytic complex CC
GO:1905368 peptidase complex CC
GO:1905369 endopeptidase complex CC
GO:1990904 ribonucleoprotein complex CC
KEGG Term Name Description
map03050 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.