Basic Information
Gene ID
gene-IMY05_017G0028800
Position
CM029815.1:2985639-3020814 (-)
35175bp
Gene Type
gene
Gene Description (Protein Product)
Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits
Organism
Also AS AT1G67120

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C0445000100 Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis
gene-IMY05_C5241000100 Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis
gene-IMY05_017G0076500 Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit

Load All Networks

Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000027 ribosomal large subunit assembly BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005509 calcium ion binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005911 cell-cell junction CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006364 rRNA processing BP
GO:0006396 RNA processing BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006996 organelle organization BP
GO:0007275 multicellular organism development BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009506 plasmodesma CC
GO:0009507 chloroplast CC
GO:0009526 plastid envelope CC
GO:0009536 plastid CC
GO:0009553 embryo sac development BP
GO:0009941 chloroplast envelope CC
GO:0009987 cellular process BP
GO:0010467 gene expression BP
GO:0016043 cellular component organization BP
GO:0016070 RNA metabolic process BP
GO:0016072 rRNA metabolic process BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0022607 cellular component assembly BP
GO:0022613 ribonucleoprotein complex biogenesis BP
GO:0022618 ribonucleoprotein complex assembly BP
GO:0030054 cell junction CC
GO:0030684 preribosome CC
GO:0030687 preribosome, large subunit precursor CC
GO:0031967 organelle envelope CC
GO:0031975 envelope CC
GO:0032501 multicellular organismal process BP
GO:0032502 developmental process BP
GO:0032991 protein-containing complex CC
GO:0034470 ncRNA processing BP
GO:0034622 protein-containing complex assembly BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034660 ncRNA metabolic process BP
GO:0040008 regulation of growth BP
GO:0042254 ribosome biogenesis BP
GO:0042255 ribosome assembly BP
GO:0042273 ribosomal large subunit biogenesis BP
GO:0043167 ion binding MF
GO:0043169 cation binding MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043933 protein-containing complex organization BP
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044434 obsolete chloroplast part CC
GO:0044435 obsolete plastid part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0046872 metal ion binding MF
GO:0048229 gametophyte development BP
GO:0048638 regulation of developmental growth BP
GO:0048856 anatomical structure development BP
GO:0050789 regulation of biological process BP
GO:0050793 regulation of developmental process BP
GO:0055044 symplast CC
GO:0065003 protein-containing complex assembly BP
GO:0065007 biological regulation BP
GO:0070925 organelle assembly BP
GO:0071704 organic substance metabolic process BP
GO:0071826 ribonucleoprotein complex subunit organization BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1990904 ribonucleoprotein complex CC
KEGG Term Name Description
map03008 Ribosome biogenesis in eukaryotes Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage.