Basic Information
Gene ID
gene-IMY05_017G0061300
Position
CM029815.1:7604324-7606919 (-)
2595bp
Gene Type
gene
Gene Description (Protein Product)
Pyruvate dehydrogenase E1 component subunit
Organism
Also AS AT2G34590

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4401000200 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
gene-IMY05_018G0090500 Belongs to the aldehyde dehydrogenase family

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0003006 developmental process involved in reproduction BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004738 pyruvate dehydrogenase activity MF
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0006082 organic acid metabolic process BP
GO:0006629 lipid metabolic process BP
GO:0006631 fatty acid metabolic process BP
GO:0006633 fatty acid biosynthetic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008270 zinc ion binding MF
GO:0008610 lipid biosynthetic process BP
GO:0009058 biosynthetic process BP
GO:0009507 chloroplast CC
GO:0009526 plastid envelope CC
GO:0009532 plastid stroma CC
GO:0009536 plastid CC
GO:0009570 chloroplast stroma CC
GO:0009856 pollination BP
GO:0009941 chloroplast envelope CC
GO:0009987 cellular process BP
GO:0010240 plastid pyruvate dehydrogenase complex CC
GO:0016053 organic acid biosynthetic process BP
GO:0016491 oxidoreductase activity MF
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor MF
GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors MF
GO:0019752 carboxylic acid metabolic process BP
GO:0022414 reproductive process BP
GO:0031967 organelle envelope CC
GO:0031975 envelope CC
GO:0032501 multicellular organismal process BP
GO:0032502 developmental process BP
GO:0032787 monocarboxylic acid metabolic process BP
GO:0032991 protein-containing complex CC
GO:0043167 ion binding MF
GO:0043169 cation binding MF
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043436 oxoacid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044255 cellular lipid metabolic process BP
GO:0044281 small molecule metabolic process BP
GO:0044283 small molecule biosynthetic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044434 obsolete chloroplast part CC
GO:0044435 obsolete plastid part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0044706 multi-multicellular organism process BP
GO:0045254 pyruvate dehydrogenase complex CC
GO:0046394 carboxylic acid biosynthetic process BP
GO:0046872 metal ion binding MF
GO:0046914 transition metal ion binding MF
GO:0048856 anatomical structure development BP
GO:0048868 pollen tube development BP
GO:0051704 obsolete multi-organism process BP
GO:0055114 obsolete oxidation-reduction process BP
GO:0071704 organic substance metabolic process BP
GO:0072330 monocarboxylic acid biosynthetic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1902494 catalytic complex CC
GO:1990204 oxidoreductase complex CC
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00620 Pyruvate metabolism -
map00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].
map00010 Glycolysis / Gluconeogenesis Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which often corresponds to operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].