PPGR - Gene Detail

Basic Information

Gene ID	gene-IMY05_017G0090200 View in Genome Browser
Position	CM029815.1:11050558-11064882 (-) 14324bp
Gene Type	gene
Gene Description (Protein Product)	Ubiquitin receptor
Organism	Salix suchowensis
Also AS	AT3G02540

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-IMY05_C4588000500 ubiquitin-60S ribosomal protein

gene-IMY05_C4625000100 Xeroderma pigmentosum G I-region

gene-IMY05_C4652000500 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0006950	response to stress	BP
GO:0008150	biological_process	BP
GO:0009266	response to temperature stimulus	BP
GO:0009409	response to cold	BP
GO:0009628	response to abiotic stimulus	BP
GO:0031593	polyubiquitin modification-dependent protein binding	MF
GO:0032182	ubiquitin-like protein binding	MF
GO:0043130	ubiquitin binding	MF
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0044877	protein-containing complex binding	MF
GO:0050896	response to stimulus	BP
GO:0070628	proteasome binding	MF
GO:0140030	modification-dependent protein binding	MF

KEGG Term	Name	Description
map04141	Protein processing in endoplasmic reticulum	The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
map03420	Nucleotide excision repair	Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar.