PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	gene-IMY05_C4238001000 View in Genome Browser
Position	JAEQKX010000594.1:44955-46594 (+) 1639bp
Gene Type	gene
Gene Description (Protein Product)	Disulfide isomerase
Organism	Salix suchowensis
Also AS	AT1G77510

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Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-IMY05_C5274000100 Calreticulin-3-like

gene-IMY05_C4620000200 Terpenoid synthase

gene-IMY05_C4761000100 Belongs to the glycosyl hydrolase 31 family

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0001666	response to hypoxia	BP
GO:0003674	molecular_function	MF
GO:0003756	protein disulfide isomerase activity	MF
GO:0003824	catalytic activity	MF
GO:0004656	procollagen-proline 4-dioxygenase activity	MF
GO:0005102	signaling receptor binding	MF
GO:0005178	integrin binding	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005576	extracellular region	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005783	endoplasmic reticulum	CC
GO:0005788	endoplasmic reticulum lumen	CC
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	CC
GO:0005886	plasma membrane	CC
GO:0006082	organic acid metabolic process	BP
GO:0006457	protein folding	BP
GO:0006464	protein modification process	BP
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006516	glycoprotein catabolic process	BP
GO:0006517	protein deglycosylation	BP
GO:0006520	amino acid metabolic process	BP
GO:0006575	cellular modified amino acid metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0007154	cell communication	BP
GO:0007165	signal transduction	BP
GO:0007166	cell surface receptor signaling pathway	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009100	glycoprotein metabolic process	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009897	external side of plasma membrane	CC
GO:0009966	regulation of signal transduction	BP
GO:0009986	cell surface	CC
GO:0009987	cellular process	BP
GO:0010033	response to organic substance	BP
GO:0010243	response to organonitrogen compound	BP
GO:0010498	proteasomal protein catabolic process	BP
GO:0010646	regulation of cell communication	BP
GO:0010941	regulation of cell death	BP
GO:0012505	endomembrane system	CC
GO:0015035	protein-disulfide reductase activity	MF
GO:0015036	disulfide oxidoreductase activity	MF
GO:0015037	protein-disulfide reductase activity	MF
GO:0016020	membrane	CC
GO:0016043	cellular component organization	BP
GO:0016222	procollagen-proline 4-dioxygenase complex	CC
GO:0016491	oxidoreductase activity	MF
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	MF
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	MF
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	MF
GO:0016853	isomerase activity	MF
GO:0016860	intramolecular oxidoreductase activity	MF
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	MF
GO:0018126	protein hydroxylation	BP
GO:0018193	peptidyl-amino acid modification	BP
GO:0018208	peptidyl-proline modification	BP
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	BP
GO:0019221	cytokine-mediated signaling pathway	BP
GO:0019471	4-hydroxyproline metabolic process	BP
GO:0019511	peptidyl-proline hydroxylation	BP
GO:0019538	protein metabolic process	BP
GO:0019752	carboxylic acid metabolic process	BP
GO:0019798	procollagen-proline dioxygenase activity	MF
GO:0019941	modification-dependent protein catabolic process	BP
GO:0022607	cellular component assembly	BP
GO:0023051	regulation of signaling	BP
GO:0023052	signaling	BP
GO:0030163	protein catabolic process	BP
GO:0030433	ubiquitin-dependent ERAD pathway	BP
GO:0031543	peptidyl-proline dioxygenase activity	MF
GO:0031545	peptidyl-proline 4-dioxygenase activity	MF
GO:0031974	membrane-enclosed lumen	CC
GO:0032501	multicellular organismal process	BP
GO:0032991	protein-containing complex	CC
GO:0033554	cellular response to stress	BP
GO:0034097	response to cytokine	BP
GO:0034377	plasma lipoprotein particle assembly	BP
GO:0034378	chylomicron assembly	BP
GO:0034379	very-low-density lipoprotein particle assembly	BP
GO:0034975	protein folding in endoplasmic reticulum	BP
GO:0034976	response to endoplasmic reticulum stress	BP
GO:0035722	interleukin-12-mediated signaling pathway	BP
GO:0035977	protein deglycosylation involved in glycoprotein catabolic process	BP
GO:0036211	protein modification process	BP
GO:0036293	response to decreased oxygen levels	BP
GO:0036294	cellular response to decreased oxygen levels	BP
GO:0036503	ERAD pathway	BP
GO:0036507	protein demannosylation	BP
GO:0036508	protein alpha-1,2-demannosylation	BP
GO:0038155	interleukin-23-mediated signaling pathway	BP
GO:0042221	response to chemical	BP
GO:0042981	regulation of apoptotic process	BP
GO:0043062	extracellular structure organization	BP
GO:0043067	regulation of programmed cell death	BP
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043412	macromolecule modification	BP
GO:0043436	oxoacid metabolic process	BP
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0043687	post-translational protein modification	BP
GO:0043900	obsolete regulation of multi-organism process	BP
GO:0043902	obsolete positive regulation of multi-organism process	BP
GO:0043903	regulation of biological process involved in symbiotic interaction	BP
GO:0043933	protein-containing complex organization	BP
GO:0044085	cellular component biogenesis	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044281	small molecule metabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044425	obsolete membrane part	CC
GO:0044432	obsolete endoplasmic reticulum part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044459	obsolete plasma membrane part	CC
GO:0044464	obsolete cell part	CC
GO:0044877	protein-containing complex binding	MF
GO:0046596	regulation of viral entry into host cell	BP
GO:0046598	positive regulation of viral entry into host cell	BP
GO:0046982	protein heterodimerization activity	MF
GO:0046983	protein dimerization activity	MF
GO:0048518	positive regulation of biological process	BP
GO:0048524	positive regulation of viral process	BP
GO:0048583	regulation of response to stimulus	BP
GO:0050789	regulation of biological process	BP
GO:0050792	regulation of viral process	BP
GO:0050794	regulation of cellular process	BP
GO:0050839	cell adhesion molecule binding	MF
GO:0050896	response to stimulus	BP
GO:0051082	unfolded protein binding	MF
GO:0051213	dioxygenase activity	MF
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0051716	cellular response to stimulus	BP
GO:0055114	obsolete oxidation-reduction process	BP
GO:0065003	protein-containing complex assembly	BP
GO:0065005	protein-lipid complex assembly	BP
GO:0065007	biological regulation	BP
GO:0070013	intracellular organelle lumen	CC
GO:0070482	response to oxygen levels	BP
GO:0070671	response to interleukin-12	BP
GO:0070887	cellular response to chemical stimulus	BP
GO:0071310	cellular response to organic substance	BP
GO:0071345	cellular response to cytokine stimulus	BP
GO:0071349	cellular response to interleukin-12	BP
GO:0071453	cellular response to oxygen levels	BP
GO:0071456	cellular response to hypoxia	BP
GO:0071704	organic substance metabolic process	BP
GO:0071825	protein-lipid complex subunit organization	BP
GO:0071827	plasma lipoprotein particle organization	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0071944	cell periphery	CC
GO:0080134	regulation of response to stress	BP
GO:0080135	regulation of cellular response to stress	BP
GO:0097006	regulation of plasma lipoprotein particle levels	BP
GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway	BP
GO:0098552	side of membrane	CC
GO:0140096	catalytic activity, acting on a protein	MF
GO:1900407	regulation of cellular response to oxidative stress	BP
GO:1901135	carbohydrate derivative metabolic process	BP
GO:1901136	carbohydrate derivative catabolic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901575	organic substance catabolic process	BP
GO:1901605	alpha-amino acid metabolic process	BP
GO:1901698	response to nitrogen compound	BP
GO:1901700	response to oxygen-containing compound	BP
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	BP
GO:1902494	catalytic complex	CC
GO:1902531	regulation of intracellular signal transduction	BP
GO:1902882	regulation of response to oxidative stress	BP
GO:1903201	regulation of oxidative stress-induced cell death	BP
GO:1903900	regulation of viral life cycle	BP
GO:1903902	positive regulation of viral life cycle	BP
GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	BP
GO:1904587	response to glycoprotein	BP
GO:1990204	oxidoreductase complex	CC
GO:2001233	regulation of apoptotic signaling pathway	BP
GO:2001242	regulation of intrinsic apoptotic signaling pathway	BP

KEGG Term	Name	Description
map04141	Protein processing in endoplasmic reticulum	The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.