Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-IMY05_C4465000300
View in Genome Browser
Position
JAEQKX010000677.1:11630-13957 (-)
2327bp
Gene Type
gene
Gene Description (Protein Product)
Telomere-length maintenance and DNA damage repair
Organism
Salix suchowensis
Also AS AT3G48190

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4770000500 repair protein
gene-IMY05_C4891000100 four-way junction helicase activity
gene-IMY05_C4715000700 Rad51

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000723 telomere maintenance BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003824 catalytic activity MF
GO:0004672 protein kinase activity MF
GO:0004674 protein serine/threonine kinase activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006275 regulation of DNA replication BP
GO:0006281 DNA repair BP
GO:0006282 regulation of DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006325 chromatin organization BP
GO:0006464 protein modification process BP
GO:0006468 protein phosphorylation BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006793 phosphorus metabolic process BP
GO:0006796 phosphate-containing compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006975 signal transduction in response to DNA damage BP
GO:0006996 organelle organization BP
GO:0007346 regulation of mitotic cell cycle BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009889 regulation of biosynthetic process BP
GO:0009891 positive regulation of biosynthetic process BP
GO:0009893 positive regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010557 positive regulation of macromolecule biosynthetic process BP
GO:0010564 regulation of cell cycle process BP
GO:0010571 positive regulation of nuclear cell cycle DNA replication BP
GO:0010604 positive regulation of macromolecule metabolic process BP
GO:0016043 cellular component organization BP
GO:0016301 kinase activity MF
GO:0016310 phosphorylation BP
GO:0016569 obsolete covalent chromatin modification BP
GO:0016570 histone modification BP
GO:0016572 obsolete histone phosphorylation BP
GO:0016740 transferase activity MF
GO:0016772 transferase activity, transferring phosphorus-containing groups MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0018105 peptidyl-serine phosphorylation BP
GO:0018193 peptidyl-amino acid modification BP
GO:0018209 peptidyl-serine modification BP
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0030174 regulation of DNA-templated DNA replication initiation BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031325 positive regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031328 positive regulation of cellular biosynthetic process BP
GO:0032200 telomere organization BP
GO:0032298 positive regulation of DNA-templated DNA replication initiation BP
GO:0033262 regulation of nuclear cell cycle DNA replication BP
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0036211 protein modification process BP
GO:0042162 telomeric DNA binding MF
GO:0042592 homeostatic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0043565 sequence-specific DNA binding MF
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044464 obsolete cell part CC
GO:0045739 positive regulation of DNA repair BP
GO:0045740 positive regulation of DNA replication BP
GO:0045787 positive regulation of cell cycle BP
GO:0045931 positive regulation of mitotic cell cycle BP
GO:0045935 positive regulation of nucleobase-containing compound metabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0048518 positive regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0048583 regulation of response to stimulus BP
GO:0048584 positive regulation of response to stimulus BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051052 regulation of DNA metabolic process BP
GO:0051054 positive regulation of DNA metabolic process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051173 positive regulation of nitrogen compound metabolic process BP
GO:0051276 chromosome organization BP
GO:0051445 regulation of meiotic cell cycle BP
GO:0051446 positive regulation of meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0051726 regulation of cell cycle BP
GO:0060249 anatomical structure homeostasis BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065007 biological regulation BP
GO:0065008 regulation of biological quality BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080090 regulation of primary metabolic process BP
GO:0080134 regulation of response to stress BP
GO:0080135 regulation of cellular response to stress BP
GO:0090068 positive regulation of cell cycle process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090329 regulation of DNA-templated DNA replication BP
GO:0097159 organic cyclic compound binding MF
GO:0140096 catalytic activity, acting on a protein MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901976 regulation of cell cycle checkpoint BP
GO:1901978 positive regulation of cell cycle checkpoint BP
GO:1904289 regulation of mitotic DNA damage checkpoint BP
GO:1904291 positive regulation of mitotic DNA damage checkpoint BP
GO:1904512 regulation of initiation of premeiotic DNA replication BP
GO:1904514 positive regulation of initiation of premeiotic DNA replication BP
GO:1990164 obsolete histone H2A phosphorylation BP
GO:1990853 obsolete histone H2A SQE motif phosphorylation BP
GO:2000001 regulation of DNA damage checkpoint BP
GO:2000003 positive regulation of DNA damage checkpoint BP
GO:2000105 positive regulation of DNA-templated DNA replication BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000241 regulation of reproductive process BP
GO:2000243 positive regulation of reproductive process BP
GO:2001020 regulation of response to DNA damage stimulus BP
GO:2001022 positive regulation of response to DNA damage stimulus BP
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.