Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-IMY05_C4485000900
View in Genome Browser
Position
JAEQKX010000696.1:52532-53811 (+)
1279bp
Gene Type
gene
Gene Description (Protein Product)
Dna mismatch repair
Organism
Salix suchowensis
Also AS AT3G18524

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4745000100 replication factor c
gene-IMY05_C4826000100 DNA ligase
gene-IMY05_C4845000200 P-loop containing nucleoside triphosphate hydrolase protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000018 regulation of DNA recombination BP
GO:0000166 nucleotide binding MF
GO:0000217 DNA secondary structure binding MF
GO:0000228 nuclear chromosome CC
GO:0000400 four-way junction DNA binding MF
GO:0000403 Y-form DNA binding MF
GO:0000404 heteroduplex DNA loop binding MF
GO:0000406 double-strand/single-strand DNA junction binding MF
GO:0000710 meiotic mismatch repair BP
GO:0000735 removal of nonhomologous ends BP
GO:0003006 developmental process involved in reproduction BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003684 damaged DNA binding MF
GO:0003690 double-stranded DNA binding MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005524 ATP binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005694 chromosome CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006260 DNA replication BP
GO:0006261 DNA-templated DNA replication BP
GO:0006275 regulation of DNA replication BP
GO:0006281 DNA repair BP
GO:0006298 mismatch repair BP
GO:0006301 postreplication repair BP
GO:0006310 DNA recombination BP
GO:0006311 meiotic gene conversion BP
GO:0006312 mitotic recombination BP
GO:0006325 chromatin organization BP
GO:0006342 heterochromatin formation BP
GO:0006355 regulation of DNA-templated transcription BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0007530 sex determination BP
GO:0007531 mating type determination BP
GO:0007533 mating type switching BP
GO:0007534 gene conversion at mating-type locus BP
GO:0008094 ATP-dependent activity, acting on DNA MF
GO:0008144 obsolete drug binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008156 negative regulation of DNA replication BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009889 regulation of biosynthetic process BP
GO:0009890 negative regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010468 regulation of gene expression BP
GO:0010520 regulation of reciprocal meiotic recombination BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010558 negative regulation of macromolecule biosynthetic process BP
GO:0010564 regulation of cell cycle process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010629 negative regulation of gene expression BP
GO:0010639 negative regulation of organelle organization BP
GO:0010948 negative regulation of cell cycle process BP
GO:0016043 cellular component organization BP
GO:0016458 obsolete gene silencing BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017076 purine nucleotide binding MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0022402 cell cycle process BP
GO:0022413 reproductive process in single-celled organism BP
GO:0022414 reproductive process BP
GO:0030154 cell differentiation BP
GO:0030466 silent mating-type cassette heterochromatin formation BP
GO:0030554 adenyl nucleotide binding MF
GO:0030983 mismatched DNA binding MF
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031327 negative regulation of cellular biosynthetic process BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032135 DNA insertion or deletion binding MF
GO:0032137 guanine/thymine mispair binding MF
GO:0032138 single base insertion or deletion binding MF
GO:0032300 mismatch repair complex CC
GO:0032301 MutSalpha complex CC
GO:0032302 MutSbeta complex CC
GO:0032502 developmental process BP
GO:0032505 reproduction of a single-celled organism BP
GO:0032553 ribonucleotide binding MF
GO:0032555 purine ribonucleotide binding MF
GO:0032559 adenyl ribonucleotide binding MF
GO:0032991 protein-containing complex CC
GO:0033043 regulation of organelle organization BP
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0035639 purine ribonucleoside triphosphate binding MF
GO:0035822 gene conversion BP
GO:0036094 small molecule binding MF
GO:0036297 interstrand cross-link repair BP
GO:0040020 regulation of meiotic nuclear division BP
GO:0040029 epigenetic regulation of gene expression BP
GO:0042623 ATP hydrolysis activity MF
GO:0043111 replication fork arrest BP
GO:0043167 ion binding MF
GO:0043168 anion binding MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043570 maintenance of DNA repeat elements BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045005 DNA-templated DNA replication maintenance of fidelity BP
GO:0045128 negative regulation of reciprocal meiotic recombination BP
GO:0045165 cell fate commitment BP
GO:0045786 negative regulation of cell cycle BP
GO:0045814 negative regulation of gene expression, epigenetic BP
GO:0045835 negative regulation of meiotic nuclear division BP
GO:0045892 negative regulation of DNA-templated transcription BP
GO:0045910 negative regulation of DNA recombination BP
GO:0045934 negative regulation of nucleobase-containing compound metabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0048869 cellular developmental process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051052 regulation of DNA metabolic process BP
GO:0051053 negative regulation of DNA metabolic process BP
GO:0051128 regulation of cellular component organization BP
GO:0051129 negative regulation of cellular component organization BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051253 negative regulation of RNA metabolic process BP
GO:0051276 chromosome organization BP
GO:0051321 meiotic cell cycle BP
GO:0051445 regulation of meiotic cell cycle BP
GO:0051447 negative regulation of meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0051726 regulation of cell cycle BP
GO:0051783 regulation of nuclear division BP
GO:0051784 negative regulation of nuclear division BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0060631 regulation of meiosis I BP
GO:0061982 meiosis I cell cycle process BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080090 regulation of primary metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090329 regulation of DNA-templated DNA replication BP
GO:0097159 organic cyclic compound binding MF
GO:0097367 carbohydrate derivative binding MF
GO:0110029 negative regulation of meiosis I BP
GO:1901265 nucleoside phosphate binding MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901576 organic substance biosynthetic process BP
GO:1902679 negative regulation of RNA biosynthetic process BP
GO:1903046 meiotic cell cycle process BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:1903507 negative regulation of nucleic acid-templated transcription BP
GO:1990391 DNA repair complex CC
GO:2000104 negative regulation of DNA-templated DNA replication BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000113 negative regulation of cellular macromolecule biosynthetic process BP
GO:2000241 regulation of reproductive process BP
GO:2000242 negative regulation of reproductive process BP
GO:2001141 regulation of RNA biosynthetic process BP
KEGG Term Name Description
map04144 Endocytosis Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.
map03430 Mismatch repair DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.