Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
gene-IMY05_C4496000500
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Position
JAEQKX010000706.1:24635-25869 (+)
1234bp
Gene Type
gene
Gene Description (Protein Product)
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle
Organism
Salix suchowensis
Also AS AT5G55190

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4830000200 CRM1 C terminal
gene-IMY05_C5045000300 RAN GTPase-activating protein
gene-IMY05_C4543000400 ARM repeat-containing protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000054 ribosomal subunit export from nucleus BP
GO:0000166 nucleotide binding MF
GO:0000459 exonucleolytic trimming involved in rRNA processing BP
GO:0000460 maturation of 5.8S rRNA BP
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) BP
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) BP
GO:0000469 cleavage involved in rRNA processing BP
GO:0001882 nucleoside binding MF
GO:0001883 purine nucleoside binding MF
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0003924 GTPase activity MF
GO:0005085 guanyl-nucleotide exchange factor activity MF
GO:0005087 guanyl-nucleotide exchange factor activity MF
GO:0005088 guanyl-nucleotide exchange factor activity MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005525 GTP binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006355 regulation of DNA-templated transcription BP
GO:0006364 rRNA processing BP
GO:0006396 RNA processing BP
GO:0006403 RNA localization BP
GO:0006405 RNA export from nucleus BP
GO:0006406 mRNA export from nucleus BP
GO:0006606 protein import into nucleus BP
GO:0006611 protein export from nucleus BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006810 transport BP
GO:0006886 intracellular protein transport BP
GO:0006913 nucleocytoplasmic transport BP
GO:0006996 organelle organization BP
GO:0006997 nucleus organization BP
GO:0007346 regulation of mitotic cell cycle BP
GO:0008104 protein localization BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008536 small GTPase binding MF
GO:0009889 regulation of biosynthetic process BP
GO:0009987 cellular process BP
GO:0010389 regulation of G2/M transition of mitotic cell cycle BP
GO:0010467 gene expression BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010564 regulation of cell cycle process BP
GO:0010948 negative regulation of cell cycle process BP
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle BP
GO:0015031 protein transport BP
GO:0015833 peptide transport BP
GO:0015931 nucleobase-containing compound transport BP
GO:0016020 membrane CC
GO:0016021 membrane CC
GO:0016043 cellular component organization BP
GO:0016070 RNA metabolic process BP
GO:0016072 rRNA metabolic process BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016973 poly(A)+ mRNA export from nucleus BP
GO:0017016 small GTPase binding MF
GO:0017038 protein import BP
GO:0017076 purine nucleotide binding MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0019001 guanyl nucleotide binding MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019899 enzyme binding MF
GO:0022613 ribonucleoprotein complex biogenesis BP
GO:0023052 signaling BP
GO:0031123 RNA 3'-end processing BP
GO:0031125 rRNA 3'-end processing BP
GO:0031224 obsolete intrinsic component of membrane CC
GO:0031267 small GTPase binding MF
GO:0031323 regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031503 protein-containing complex localization BP
GO:0031935 obsolete regulation of chromatin silencing BP
GO:0031938 obsolete regulation of chromatin silencing at telomere BP
GO:0032549 ribonucleoside binding MF
GO:0032550 purine ribonucleoside binding MF
GO:0032553 ribonucleotide binding MF
GO:0032555 purine ribonucleotide binding MF
GO:0032561 guanyl ribonucleotide binding MF
GO:0033036 macromolecule localization BP
GO:0033043 regulation of organelle organization BP
GO:0033044 regulation of chromosome organization BP
GO:0033365 protein localization to organelle BP
GO:0033750 ribosome localization BP
GO:0034470 ncRNA processing BP
GO:0034504 protein localization to nucleus BP
GO:0034613 protein localization BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034660 ncRNA metabolic process BP
GO:0035639 purine ribonucleoside triphosphate binding MF
GO:0036094 small molecule binding MF
GO:0042254 ribosome biogenesis BP
GO:0042886 amide transport BP
GO:0043167 ion binding MF
GO:0043168 anion binding MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043628 regulatory ncRNA 3'-end processing BP
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044425 obsolete membrane part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044464 obsolete cell part CC
GO:0045184 establishment of protein localization BP
GO:0045786 negative regulation of cell cycle BP
GO:0045930 negative regulation of mitotic cell cycle BP
GO:0046483 heterocycle metabolic process BP
GO:0046907 intracellular transport BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0050657 nucleic acid transport BP
GO:0050658 RNA transport BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0051020 GTPase binding MF
GO:0051028 mRNA transport BP
GO:0051128 regulation of cellular component organization BP
GO:0051168 nuclear export BP
GO:0051169 nuclear transport BP
GO:0051170 import into nucleus BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051179 localization BP
GO:0051234 establishment of localization BP
GO:0051236 establishment of RNA localization BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051640 organelle localization BP
GO:0051641 cellular localization BP
GO:0051649 establishment of localization in cell BP
GO:0051656 establishment of organelle localization BP
GO:0051726 regulation of cell cycle BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0060968 obsolete regulation of gene silencing BP
GO:0065007 biological regulation BP
GO:0065009 regulation of molecular function BP
GO:0070727 cellular macromolecule localization BP
GO:0071166 ribonucleoprotein complex localization BP
GO:0071426 obsolete ribonucleoprotein complex export from nucleus BP
GO:0071427 obsolete mRNA-containing ribonucleoprotein complex export from nucleus BP
GO:0071428 obsolete rRNA-containing ribonucleoprotein complex export from nucleus BP
GO:0071702 organic substance transport BP
GO:0071704 organic substance metabolic process BP
GO:0071705 nitrogen compound transport BP
GO:0071840 cellular component organization or biogenesis BP
GO:0072594 establishment of protein localization to organelle BP
GO:0080090 regulation of primary metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0090501 RNA phosphodiester bond hydrolysis BP
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic BP
GO:0097159 organic cyclic compound binding MF
GO:0097367 carbohydrate derivative binding MF
GO:0098772 molecular function regulator activity MF
GO:1901265 nucleoside phosphate binding MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901987 regulation of cell cycle phase transition BP
GO:1901988 negative regulation of cell cycle phase transition BP
GO:1901990 regulation of mitotic cell cycle phase transition BP
GO:1901991 negative regulation of mitotic cell cycle phase transition BP
GO:1902275 regulation of chromatin organization BP
GO:1902749 regulation of cell cycle G2/M phase transition BP
GO:1902750 negative regulation of cell cycle G2/M phase transition BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2001141 regulation of RNA biosynthetic process BP
KEGG Term Name Description
map03013 RNA transport RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation.
map03008 Ribosome biogenesis in eukaryotes Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage.