PPGR - Gene Detail

Basic Information

Gene ID	gene-IMY05_C4695000200 View in Genome Browser
Position	JAEQKX010000886.1:16132-18878 (+) 2746bp
Gene Type	gene
Gene Description (Protein Product)	Cullin-domain-containing protein
Organism	Salix suchowensis
Also AS	AT1G26830

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-IMY05_C4876000300 Anaphase-promoting complex subunit 11 RING-H2 finger

gene-IMY05_C4879000700 Belongs to the ubiquitin-conjugating enzyme family

gene-IMY05_C4699000100 Domain of Unknown Function (DUF913)

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0000151	ubiquitin ligase complex	CC
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004842	ubiquitin-protein transferase activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005737	cytoplasm	CC
GO:0006464	protein modification process	BP
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009987	cellular process	BP
GO:0010498	proteasomal protein catabolic process	BP
GO:0016567	protein ubiquitination	BP
GO:0016740	transferase activity	MF
GO:0019005	SCF ubiquitin ligase complex	CC
GO:0019538	protein metabolic process	BP
GO:0019787	ubiquitin-like protein transferase activity	MF
GO:0019899	enzyme binding	MF
GO:0019941	modification-dependent protein catabolic process	BP
GO:0030163	protein catabolic process	BP
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	BP
GO:0031461	cullin-RING ubiquitin ligase complex	CC
GO:0031463	Cul3-RING ubiquitin ligase complex	CC
GO:0031625	ubiquitin protein ligase binding	MF
GO:0032446	protein modification by small protein conjugation	BP
GO:0032991	protein-containing complex	CC
GO:0036211	protein modification process	BP
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043412	macromolecule modification	BP
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044389	ubiquitin-like protein ligase binding	MF
GO:0044424	obsolete intracellular part	CC
GO:0044464	obsolete cell part	CC
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0071704	organic substance metabolic process	BP
GO:0140096	catalytic activity, acting on a protein	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901575	organic substance catabolic process	BP
GO:1902494	catalytic complex	CC
GO:1990234	transferase complex	CC

KEGG Term	Name	Description
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.