Basic Information
Gene ID
gene-IMY05_C4696000200
Position
JAEQKX010000887.1:3051-5298 (+)
2247bp
Gene Type
gene
Gene Description (Protein Product)
DNA polymerase alpha catalytic subunit
Organism
Also AS AT5G67100

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4903000200 Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases
gene-IMY05_C4903000300 Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000228 nuclear chromosome CC
GO:0000278 mitotic cell cycle BP
GO:0000428 DNA-directed RNA polymerase complex CC
GO:0000726 obsolete non-recombinational repair BP
GO:0000731 DNA synthesis involved in DNA repair BP
GO:0000734 gene conversion at mating-type locus BP
GO:0000781 chromosome, telomeric region CC
GO:0000784 chromosome, telomeric region CC
GO:0000785 chromatin CC
GO:0000790 chromatin CC
GO:0003006 developmental process involved in reproduction BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003682 chromatin binding MF
GO:0003688 DNA replication origin binding MF
GO:0003690 double-stranded DNA binding MF
GO:0003697 single-stranded DNA binding MF
GO:0003824 catalytic activity MF
GO:0003887 DNA-directed DNA polymerase activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005657 replication fork CC
GO:0005658 alpha DNA polymerase:primase complex CC
GO:0005694 chromosome CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006260 DNA replication BP
GO:0006261 DNA-templated DNA replication BP
GO:0006269 DNA replication, synthesis of RNA primer BP
GO:0006270 DNA replication initiation BP
GO:0006271 DNA strand elongation involved in DNA replication BP
GO:0006272 leading strand elongation BP
GO:0006273 lagging strand elongation BP
GO:0006278 RNA-templated DNA biosynthetic process BP
GO:0006279 premeiotic DNA replication BP
GO:0006281 DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006303 double-strand break repair via nonhomologous end joining BP
GO:0006310 DNA recombination BP
GO:0006312 mitotic recombination BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0007049 cell cycle BP
GO:0007530 sex determination BP
GO:0007531 mating type determination BP
GO:0007533 mating type switching BP
GO:0007534 gene conversion at mating-type locus BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009987 cellular process BP
GO:0016070 RNA metabolic process BP
GO:0016740 transferase activity MF
GO:0016772 transferase activity, transferring phosphorus-containing groups MF
GO:0016779 nucleotidyltransferase activity MF
GO:0018130 heterocycle biosynthetic process BP
GO:0019438 aromatic compound biosynthetic process BP
GO:0022402 cell cycle process BP
GO:0022413 reproductive process in single-celled organism BP
GO:0022414 reproductive process BP
GO:0022616 DNA strand elongation BP
GO:0030154 cell differentiation BP
GO:0030880 RNA polymerase complex CC
GO:0030894 replisome CC
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032502 developmental process BP
GO:0032505 reproduction of a single-celled organism BP
GO:0032774 RNA biosynthetic process BP
GO:0032991 protein-containing complex CC
GO:0032993 protein-DNA complex CC
GO:0033260 nuclear DNA replication BP
GO:0033554 cellular response to stress BP
GO:0034061 DNA polymerase activity MF
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0034654 nucleobase-containing compound biosynthetic process BP
GO:0035822 gene conversion BP
GO:0035861 site of double-strand break CC
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043565 sequence-specific DNA binding MF
GO:0043596 nuclear replication fork CC
GO:0043601 nuclear replisome CC
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044271 cellular nitrogen compound biosynthetic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044427 obsolete chromosomal part CC
GO:0044428 obsolete nuclear part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044454 obsolete nuclear chromosome part CC
GO:0044464 obsolete cell part CC
GO:0044786 cell cycle DNA replication BP
GO:0045165 cell fate commitment BP
GO:0046483 heterocycle metabolic process BP
GO:0048869 cellular developmental process BP
GO:0050896 response to stimulus BP
GO:0051321 meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0055029 nuclear DNA-directed RNA polymerase complex CC
GO:0061695 transferase complex, transferring phosphorus-containing groups CC
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0071897 DNA biosynthetic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090734 site of DNA damage CC
GO:0097159 organic cyclic compound binding MF
GO:0098687 chromosomal region CC
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901362 organic cyclic compound biosynthetic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901576 organic substance biosynthetic process BP
GO:1902292 cell cycle DNA replication initiation BP
GO:1902295 synthesis of RNA primer involved in cell cycle DNA replication BP
GO:1902315 nuclear cell cycle DNA replication initiation BP
GO:1902318 synthesis of RNA primer involved in nuclear cell cycle DNA replication BP
GO:1902494 catalytic complex CC
GO:1902969 mitotic DNA replication BP
GO:1902975 mitotic DNA replication initiation BP
GO:1902981 synthesis of RNA primer involved in mitotic DNA replication BP
GO:1903046 meiotic cell cycle process BP
GO:1903047 mitotic cell cycle process BP
GO:1990234 transferase complex CC
GO:1990837 sequence-specific double-stranded DNA binding MF
KEGG Term Name Description
map03030 DNA replication A complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM complex) precedes the DNA synthetic machinery and unwinds the duplex parental DNA in cooperation with the SSB or RPA. On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication occurs discontinuously by synthesis and joining of short Okazaki fragments. In prokaryotes, the leading strand replication apparatus consists of a DNA polymerase (pol III core), a sliding clamp (beta), and a clamp loader (gamma delta complex). The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA primer is removed either by an RNase H or by the 5 to 3 exonuclease activity of DNA pol I, and the DNA ligase joins the Okazaki fragments. In eukaryotes, three DNA polymerases (alpha, delta, and epsilon) have been identified. DNA primase forms a permanent complex with DNA polymerase alpha. PCNA and RFC function as a clamp and a clamp loader. FEN 1 and RNase H1 remove the RNA from the Okazaki fragments and DNA ligase I joins the DNA.