Basic Information
Gene ID
Position
Scaffold_152400:666591155-666591965 (-)
810bp
Gene Type
gene
Gene Description (Protein Product)
Neutral ceramidase-like
Organism
Also AS AT2G38010

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
SESE_124035.g Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide
SESE_129930.g Long chain base biosynthesis protein
SESE_146426.g protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex (By similarity). The CSN complex is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. Involved in CSN's deneddylation derubylation activity. Required for the deneddylation of all cullins. Essential for the structural integrity of the CSN holocomplex
Regulatory gene
SESE_001250.g NAC domain-containing protein
SESE_007476.g dof zinc finger protein
SESE_020899.g transcription, DNA-templated

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005773 vacuole CC
GO:0005774 vacuolar membrane CC
GO:0005783 endoplasmic reticulum CC
GO:0005794 Golgi apparatus CC
GO:0006950 response to stress BP
GO:0006979 response to oxidative stress BP
GO:0008150 biological_process BP
GO:0009987 cellular process BP
GO:0012505 endomembrane system CC
GO:0016020 membrane CC
GO:0019725 cellular homeostasis BP
GO:0031090 organelle membrane CC
GO:0033554 cellular response to stress BP
GO:0034599 cellular response to oxidative stress BP
GO:0042221 response to chemical BP
GO:0042592 homeostatic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044437 obsolete vacuolar part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0048878 chemical homeostasis BP
GO:0050896 response to stimulus BP
GO:0051716 cellular response to stimulus BP
GO:0055082 intracellular chemical homeostasis BP
GO:0055088 lipid homeostasis BP
GO:0065007 biological regulation BP
GO:0065008 regulation of biological quality BP
GO:0070887 cellular response to chemical stimulus BP
GO:0090156 intracellular sphingolipid homeostasis BP
GO:0098588 bounding membrane of organelle CC
GO:0098805 membrane CC
KEGG Term Name Description
map01100 Metabolic pathways -
map00600 Sphingolipid metabolism -