PPGR - Gene Detail

Basic Information

Gene ID	SESE_123877.g View in Genome Browser
Position	Scaffold_146464:11291-17887 (+) 6596bp
Gene Type	gene
Gene Description (Protein Product)	Belongs to the thiamine pyrophosphokinase family
Organism	Sequoia sempervirens
Also AS	AT2G44750

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

SESE_148407.g Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance

SESE_146456.g Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance

SESE_148565.g Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance

Regulatory gene

SESE_004082.g Myb family transcription factor

SESE_007476.g dof zinc finger protein

SESE_009402.g PHR1-LIKE 1-like

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004788	thiamine diphosphokinase activity	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006732	obsolete coenzyme metabolic process	BP
GO:0006766	vitamin metabolic process	BP
GO:0006767	water-soluble vitamin metabolic process	BP
GO:0006772	thiamine metabolic process	BP
GO:0006790	sulfur compound metabolic process	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009058	biosynthetic process	BP
GO:0009108	obsolete coenzyme biosynthetic process	BP
GO:0009229	thiamine diphosphate biosynthetic process	BP
GO:0009987	cellular process	BP
GO:0016740	transferase activity	MF
GO:0016772	transferase activity, transferring phosphorus-containing groups	MF
GO:0016778	diphosphotransferase activity	MF
GO:0017144	xenobiotic metabolic process	BP
GO:0018130	heterocycle biosynthetic process	BP
GO:0019438	aromatic compound biosynthetic process	BP
GO:0019637	organophosphate metabolic process	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0042357	thiamine diphosphate metabolic process	BP
GO:0042723	thiamine-containing compound metabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044271	cellular nitrogen compound biosynthetic process	BP
GO:0044272	sulfur compound biosynthetic process	BP
GO:0044281	small molecule metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0051186	obsolete cofactor metabolic process	BP
GO:0051188	obsolete cofactor biosynthetic process	BP
GO:0071704	organic substance metabolic process	BP
GO:0072527	pyrimidine-containing compound metabolic process	BP
GO:0072528	pyrimidine-containing compound biosynthetic process	BP
GO:0090407	organophosphate biosynthetic process	BP
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901362	organic cyclic compound biosynthetic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901566	organonitrogen compound biosynthetic process	BP
GO:1901576	organic substance biosynthetic process	BP

KEGG Term	Name	Description
map01100	Metabolic pathways	-
map00730	Thiamine metabolism	-