Basic Information
Gene ID
gene-LOC107432679
Position
NC_063298.1:13696672-13702334 (-)
5662bp
Gene Type
gene
Gene Description (Protein Product)
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors; where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state; facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently; the homodimer reverts towards the open dimer state; lowering its affinity for the membrane-bound receptor; and returning it to the cytosol to initiate a new round of targeting
Organism
Also AS AT1G01910

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-LOC107432777 leucine-rich repeat extensin-like protein
gene-LOC125420014 Signal recognition particle receptor subunit

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)