Basic Information
Gene ID
gene-LOC107434442
Position
NC_063296.1:18878710-18899370 (+)
20660bp
Gene Type
gene
Gene Description (Protein Product)
THO complex subunit
Organism
Also AS AT1G24706

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-LOC125418397 Belongs to the MCM family
gene-LOC112492789 Belongs to the MCM family

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000346 transcription export complex CC
GO:0000347 THO complex CC
GO:0000445 THO complex part of transcription export complex CC
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003723 RNA binding MF
GO:0003729 mRNA binding MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006396 RNA processing BP
GO:0006403 RNA localization BP
GO:0006405 RNA export from nucleus BP
GO:0006406 mRNA export from nucleus BP
GO:0006611 protein export from nucleus BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006810 transport BP
GO:0006886 intracellular protein transport BP
GO:0006913 nucleocytoplasmic transport BP
GO:0008104 protein localization BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010033 response to organic substance BP
GO:0010467 gene expression BP
GO:0010468 regulation of gene expression BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010608 post-transcriptional regulation of gene expression BP
GO:0010629 negative regulation of gene expression BP
GO:0014070 response to organic cyclic compound BP
GO:0015031 protein transport BP
GO:0015833 peptide transport BP
GO:0015931 nucleobase-containing compound transport BP
GO:0016070 RNA metabolic process BP
GO:0016441 post-transcriptional gene silencing BP
GO:0016458 obsolete gene silencing BP
GO:0016604 nuclear body CC
GO:0016607 nuclear speck CC
GO:0019222 regulation of metabolic process BP
GO:0031047 RNA-mediated gene silencing BP
GO:0031050 ncRNA processing BP
GO:0031503 protein-containing complex localization BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032991 protein-containing complex CC
GO:0033036 macromolecule localization BP
GO:0034613 protein localization BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035194 RNA-mediated post-transcriptional gene silencing BP
GO:0035195 miRNA-mediated gene silencing BP
GO:0035196 miRNA processing BP
GO:0040029 epigenetic regulation of gene expression BP
GO:0042221 response to chemical BP
GO:0042886 amide transport BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043331 response to dsRNA BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044451 obsolete nucleoplasm part CC
GO:0044464 obsolete cell part CC
GO:0045184 establishment of protein localization BP
GO:0046483 heterocycle metabolic process BP
GO:0046907 intracellular transport BP
GO:0048519 negative regulation of biological process BP
GO:0050657 nucleic acid transport BP
GO:0050658 RNA transport BP
GO:0050789 regulation of biological process BP
GO:0050896 response to stimulus BP
GO:0051028 mRNA transport BP
GO:0051168 nuclear export BP
GO:0051169 nuclear transport BP
GO:0051179 localization BP
GO:0051234 establishment of localization BP
GO:0051236 establishment of RNA localization BP
GO:0051641 cellular localization BP
GO:0051649 establishment of localization in cell BP
GO:0051716 cellular response to stimulus BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0070727 cellular macromolecule localization BP
GO:0070887 cellular response to chemical stimulus BP
GO:0070918 regulatory ncRNA processing BP
GO:0071166 ribonucleoprotein complex localization BP
GO:0071310 cellular response to organic substance BP
GO:0071359 cellular response to dsRNA BP
GO:0071407 cellular response to organic cyclic compound BP
GO:0071426 obsolete ribonucleoprotein complex export from nucleus BP
GO:0071427 obsolete mRNA-containing ribonucleoprotein complex export from nucleus BP
GO:0071702 organic substance transport BP
GO:0071704 organic substance metabolic process BP
GO:0071705 nitrogen compound transport BP
GO:0090304 nucleic acid metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901698 response to nitrogen compound BP
GO:1901699 cellular response to nitrogen compound BP
GO:1990428 miRNA transport BP
KEGG Term Name Description
map03040 Spliceosome After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified.
map03013 RNA transport RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation.