Basic Information
Gene ID
gene-LOC125418191
Position
NC_063295.1:6624888-6629430 (+)
4542bp
Gene Type
gene
Gene Description (Protein Product)
GPI transamidase component
Organism
Also AS AT3G07140

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-LOC125421779 Glycosylphosphatidylinositol anchor attachment 1
gene-LOC125424034 CYSTM1 family protein A-like
gene-LOC125422520 mitochondrial transcription termination factor family protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005783 endoplasmic reticulum CC
GO:0005789 endoplasmic reticulum membrane CC
GO:0006464 protein modification process BP
GO:0006497 protein lipidation BP
GO:0006505 GPI anchor metabolic process BP
GO:0006506 GPI anchor biosynthetic process BP
GO:0006629 lipid metabolic process BP
GO:0006643 membrane lipid metabolic process BP
GO:0006644 phospholipid metabolic process BP
GO:0006650 glycerophospholipid metabolic process BP
GO:0006661 phosphatidylinositol biosynthetic process BP
GO:0006664 glycolipid metabolic process BP
GO:0006793 phosphorus metabolic process BP
GO:0006796 phosphate-containing compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006915 apoptotic process BP
GO:0007275 multicellular organism development BP
GO:0007399 nervous system development BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008219 cell death BP
GO:0008610 lipid biosynthetic process BP
GO:0008654 phospholipid biosynthetic process BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009247 glycolipid biosynthetic process BP
GO:0009987 cellular process BP
GO:0012501 programmed cell death BP
GO:0012505 endomembrane system CC
GO:0016020 membrane CC
GO:0016021 membrane CC
GO:0016255 attachment of GPI anchor to protein BP
GO:0019538 protein metabolic process BP
GO:0019637 organophosphate metabolic process BP
GO:0022008 neurogenesis BP
GO:0030154 cell differentiation BP
GO:0030176 obsolete integral component of endoplasmic reticulum membrane CC
GO:0030182 neuron differentiation BP
GO:0031224 obsolete intrinsic component of membrane CC
GO:0031227 obsolete intrinsic component of endoplasmic reticulum membrane CC
GO:0031410 cytoplasmic vesicle CC
GO:0031982 vesicle CC
GO:0031984 organelle subcompartment CC
GO:0032501 multicellular organismal process BP
GO:0032502 developmental process BP
GO:0032991 protein-containing complex CC
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0036211 protein modification process BP
GO:0042157 lipoprotein metabolic process BP
GO:0042158 lipoprotein biosynthetic process BP
GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network CC
GO:0042765 GPI-anchor transamidase complex CC
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044255 cellular lipid metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044425 obsolete membrane part CC
GO:0044432 obsolete endoplasmic reticulum part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045017 glycerolipid biosynthetic process BP
GO:0046467 membrane lipid biosynthetic process BP
GO:0046474 glycerophospholipid biosynthetic process BP
GO:0046486 glycerolipid metabolic process BP
GO:0046488 phosphatidylinositol metabolic process BP
GO:0048699 generation of neurons BP
GO:0048731 system development BP
GO:0048856 anatomical structure development BP
GO:0048869 cellular developmental process BP
GO:0051402 neuron apoptotic process BP
GO:0070997 neuron death BP
GO:0071704 organic substance metabolic process BP
GO:0090407 organophosphate biosynthetic process BP
GO:0097708 intracellular vesicle CC
GO:0098796 membrane protein complex CC
GO:0098827 endoplasmic reticulum subcompartment CC
GO:1901135 carbohydrate derivative metabolic process BP
GO:1901137 carbohydrate derivative biosynthetic process BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901566 organonitrogen compound biosynthetic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1902494 catalytic complex CC
GO:1903509 liposaccharide metabolic process BP
KEGG Term Name Description
map01100 Metabolic pathways -
map00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored proteins have been identified in many eukaryotes ranging from protozoa and fungi to mammals. All protein-linked GPI anchors share a common core structure, characterized by the substructure Man (a1-4) GlcN (a1-6) myo-inositol-1P-lipid. Biosynthesis of GPI anchors proceeds in three stages: (i) preassembly of a GPI precursor in the ER membrane, (ii) attachment of the GPI to the C-terminus of a newly synthesized protein in the lumen of the ER, and (iii) lipid remodeling and/or carbohydrate side-chain modifications in the ER and the Golgi. Defects of GPI anchor biosynthesis gene result in a genetic disorder, paroxysmal nocturnal hemoglobinuria.