Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
gene-LOC125423478
View in Genome Browser
Position
NC_063293.1:842290-844849 (+)
2559bp
Gene Type
gene
Gene Description (Protein Product)
Bifunctional DNA N-glycosylase with associated apurinic apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER); the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond; leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines
Organism
Ziziphus jujuba
Also AS AT2G31450

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-LOC125424251 Ribosome-recycling factor
gene-LOC125424046 Fumarate hydratase
gene-LOC125423804 Belongs to the BolA IbaG family
Regulatory gene
gene-LOC107403899 dof zinc finger protein
gene-LOC107404240 Dof zinc finger protein
gene-LOC107405930 transcription factor

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000702 oxidized base lesion DNA N-glycosylase activity MF
GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity MF
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005783 endoplasmic reticulum CC
GO:0005911 cell-cell junction CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006284 base-excision repair BP
GO:0006285 base-excision repair, AP site formation BP
GO:0006289 nucleotide-excision repair BP
GO:0006296 obsolete nucleotide-excision repair, DNA incision, 5'-to lesion BP
GO:0006464 protein modification process BP
GO:0006479 protein methylation BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008168 methyltransferase activity MF
GO:0008170 N-methyltransferase activity MF
GO:0008213 protein alkylation BP
GO:0008276 protein methyltransferase activity MF
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity MF
GO:0009295 nucleoid CC
GO:0009506 plasmodesma CC
GO:0009507 chloroplast CC
GO:0009532 plastid stroma CC
GO:0009536 plastid CC
GO:0009570 chloroplast stroma CC
GO:0009987 cellular process BP
GO:0012505 endomembrane system CC
GO:0016278 lysine N-methyltransferase activity MF
GO:0016279 protein-lysine N-methyltransferase activity MF
GO:0016740 transferase activity MF
GO:0016741 transferase activity, transferring one-carbon groups MF
GO:0016787 hydrolase activity MF
GO:0016798 hydrolase activity, acting on glycosyl bonds MF
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds MF
GO:0018022 peptidyl-lysine methylation BP
GO:0018193 peptidyl-amino acid modification BP
GO:0018205 peptidyl-lysine modification BP
GO:0019104 DNA N-glycosylase activity MF
GO:0019538 protein metabolic process BP
GO:0030054 cell junction CC
GO:0032259 methylation BP
GO:0033554 cellular response to stress BP
GO:0033683 obsolete nucleotide-excision repair, DNA incision BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0036211 protein modification process BP
GO:0042644 chloroplast nucleoid CC
GO:0042646 plastid nucleoid CC
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0043414 macromolecule methylation BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044434 obsolete chloroplast part CC
GO:0044435 obsolete plastid part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0050896 response to stimulus BP
GO:0051716 cellular response to stimulus BP
GO:0055044 symplast CC
GO:0071704 organic substance metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0140096 catalytic activity, acting on a protein MF
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901564 organonitrogen compound metabolic process BP
KEGG Term Name Description
map03410 Base excision repair Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.