Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000278 | mitotic cell cycle | BP |
| GO:0000280 | nuclear division | BP |
| GO:0000815 | ESCRT III complex | CC |
| GO:0003674 | molecular_function | MF |
| GO:0005215 | transporter activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005634 | nucleus | CC |
| GO:0005635 | nuclear envelope | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005768 | endosome | CC |
| GO:0006810 | transport | BP |
| GO:0006996 | organelle organization | BP |
| GO:0006997 | nucleus organization | BP |
| GO:0006998 | nuclear envelope organization | BP |
| GO:0007034 | vacuolar transport | BP |
| GO:0007049 | cell cycle | BP |
| GO:0008104 | protein localization | BP |
| GO:0008150 | biological_process | BP |
| GO:0008565 | obsolete protein transporter activity | MF |
| GO:0009987 | cellular process | BP |
| GO:0010008 | endosome membrane | CC |
| GO:0010256 | endomembrane system organization | BP |
| GO:0010458 | exit from mitosis | BP |
| GO:0012505 | endomembrane system | CC |
| GO:0015031 | protein transport | BP |
| GO:0015833 | peptide transport | BP |
| GO:0016020 | membrane | CC |
| GO:0016043 | cellular component organization | BP |
| GO:0016192 | vesicle-mediated transport | BP |
| GO:0022402 | cell cycle process | BP |
| GO:0031090 | organelle membrane | CC |
| GO:0031410 | cytoplasmic vesicle | CC |
| GO:0031468 | nuclear membrane reassembly | BP |
| GO:0031967 | organelle envelope | CC |
| GO:0031975 | envelope | CC |
| GO:0031982 | vesicle | CC |
| GO:0032991 | protein-containing complex | CC |
| GO:0033036 | macromolecule localization | BP |
| GO:0036452 | ESCRT complex | CC |
| GO:0042886 | amide transport | BP |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044425 | obsolete membrane part | CC |
| GO:0044428 | obsolete nuclear part | CC |
| GO:0044433 | obsolete cytoplasmic vesicle part | CC |
| GO:0044440 | obsolete endosomal part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0044770 | cell cycle phase transition | BP |
| GO:0044772 | mitotic cell cycle phase transition | BP |
| GO:0045184 | establishment of protein localization | BP |
| GO:0045324 | late endosome to vacuole transport | BP |
| GO:0046907 | intracellular transport | BP |
| GO:0048285 | organelle fission | BP |
| GO:0051179 | localization | BP |
| GO:0051234 | establishment of localization | BP |
| GO:0051641 | cellular localization | BP |
| GO:0051649 | establishment of localization in cell | BP |
| GO:0061024 | membrane organization | BP |
| GO:0071702 | organic substance transport | BP |
| GO:0071705 | nitrogen compound transport | BP |
| GO:0071840 | cellular component organization or biogenesis | BP |
| GO:0097708 | intracellular vesicle | CC |
| GO:0098588 | bounding membrane of organelle | CC |
| GO:0098796 | membrane protein complex | CC |
| GO:0098805 | membrane | CC |
| GO:0140014 | mitotic nuclear division | BP |
| GO:1903047 | mitotic cell cycle process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map04144 | Endocytosis | Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type. |