PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	Pop_A14G000670 View in Genome Browser
Position	chrA14:9837407-9844091 (+) 6684bp
Gene Type	gene
Gene Description (Protein Product)	mismatch repair
Organism	Populus alba x Populus glandulosa
Also AS	Potri.014G130800AT4G02460Potri.014G130800.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	Pop_G05G018031 DNA mismatch repair protein Pop_G06G051248 DNA mismatch repair protein Pop_G04G079211 Smr domain
Regulatory gene	Pop_A01G004199 GAGA binding protein-like family Pop_A02G005181 Protein BASIC PENTACYSTEINE6-like Pop_A04G028302 Protein BASIC PENTACYSTEINE4-like

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0002200	somatic diversification of immune receptors	BP
GO:0002376	immune system process	BP
GO:0002377	immunoglobulin production	BP
GO:0002440	production of molecular mediator of immune response	BP
GO:0002520	immune system development	BP
GO:0002566	somatic diversification of immune receptors via somatic mutation	BP
GO:0003006	developmental process involved in reproduction	BP
GO:0003674	molecular_function	MF
GO:0003676	nucleic acid binding	MF
GO:0003677	DNA binding	MF
GO:0003690	double-stranded DNA binding	MF
GO:0003697	single-stranded DNA binding	MF
GO:0003824	catalytic activity	MF
GO:0004518	nuclease activity	MF
GO:0004519	endonuclease activity	MF
GO:0005488	binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0005856	cytoskeleton	CC
GO:0005886	plasma membrane	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006281	DNA repair	BP
GO:0006298	mismatch repair	BP
GO:0006310	DNA recombination	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0007275	multicellular organism development	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009555	pollen development	BP
GO:0009791	post-embryonic development	BP
GO:0009987	cellular process	BP
GO:0010154	fruit development	BP
GO:0015630	microtubule cytoskeleton	CC
GO:0016020	membrane	CC
GO:0016445	somatic diversification of immunoglobulins	BP
GO:0016446	somatic hypermutation of immunoglobulin genes	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016787	hydrolase activity	MF
GO:0016788	hydrolase activity, acting on ester bonds	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0016887	ATP hydrolysis activity	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0022414	reproductive process	BP
GO:0030983	mismatched DNA binding	MF
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0032135	DNA insertion or deletion binding	MF
GO:0032138	single base insertion or deletion binding	MF
GO:0032300	mismatch repair complex	CC
GO:0032389	MutLalpha complex	CC
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0032991	protein-containing complex	CC
GO:0033554	cellular response to stress	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0035770	ribonucleoprotein granule	CC
GO:0036464	cytoplasmic ribonucleoprotein granule	CC
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0048229	gametophyte development	BP
GO:0048316	seed development	BP
GO:0048608	reproductive structure development	BP
GO:0048731	system development	BP
GO:0048856	anatomical structure development	BP
GO:0050896	response to stimulus	BP
GO:0051716	cellular response to stimulus	BP
GO:0061458	reproductive system development	BP
GO:0070013	intracellular organelle lumen	CC
GO:0071704	organic substance metabolic process	BP
GO:0071944	cell periphery	CC
GO:0090304	nucleic acid metabolic process	BP
GO:0090305	nucleic acid phosphodiester bond hydrolysis	BP
GO:0097159	organic cyclic compound binding	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1990391	DNA repair complex	CC
GO:1990904	ribonucleoprotein complex	CC

KEGG Term	Name	Description
map03430	Mismatch repair	DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.