Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0003779 | actin binding | MF |
| GO:0003785 | actin monomer binding | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0005488 | binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005886 | plasma membrane | CC |
| GO:0006629 | lipid metabolic process | BP |
| GO:0006644 | phospholipid metabolic process | BP |
| GO:0006650 | glycerophospholipid metabolic process | BP |
| GO:0006793 | phosphorus metabolic process | BP |
| GO:0006796 | phosphate-containing compound metabolic process | BP |
| GO:0008092 | cytoskeletal protein binding | MF |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0016020 | membrane | CC |
| GO:0016301 | kinase activity | MF |
| GO:0016307 | phosphatidylinositol phosphate kinase activity | MF |
| GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity | MF |
| GO:0016310 | phosphorylation | BP |
| GO:0016740 | transferase activity | MF |
| GO:0016772 | transferase activity, transferring phosphorus-containing groups | MF |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | MF |
| GO:0019637 | organophosphate metabolic process | BP |
| GO:0030258 | lipid modification | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044255 | cellular lipid metabolic process | BP |
| GO:0044464 | obsolete cell part | CC |
| GO:0044877 | protein-containing complex binding | MF |
| GO:0046486 | glycerolipid metabolic process | BP |
| GO:0046488 | phosphatidylinositol metabolic process | BP |
| GO:0046834 | lipid phosphorylation | BP |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | BP |
| GO:0051015 | actin filament binding | MF |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0071944 | cell periphery | CC |
| KEGG Term | Name | Description |
|---|---|---|
| map04144 | Endocytosis | Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type. |
| map04070 | Phosphatidylinositol signaling system | - |
| map01100 | Metabolic pathways | - |
| map00562 | Inositol phosphate metabolism | - |