Basic Information
Gene ID
AALBA5B1156530
Position
aalba5_s00222826:6181-6920 (+)
739bp
Gene Type
gene
Gene Description (Protein Product)
DNA mismatch repair protein
Organism
Also AS AT4G09140

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
AALBA5B827178 DNA mismatch repair
AALBA5B175483 Component of the post-replicative DNA mismatch repair system (MMR)
AALBA5B307332 Component of the post-replicative DNA mismatch repair system (MMR)
Regulatory gene
AALBA5B002813 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
AALBA5B023305 dof zinc finger protein
AALBA5B034007 atrl6,rl6,rsm3

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000228 nuclear chromosome CC
GO:0000785 chromatin CC
GO:0000790 chromatin CC
GO:0000793 condensed chromosome CC
GO:0000794 condensed nuclear chromosome CC
GO:0000795 synaptonemal complex CC
GO:0002200 somatic diversification of immune receptors BP
GO:0002376 immune system process BP
GO:0002377 immunoglobulin production BP
GO:0002440 production of molecular mediator of immune response BP
GO:0002520 immune system development BP
GO:0002566 somatic diversification of immune receptors via somatic mutation BP
GO:0003006 developmental process involved in reproduction BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003697 single-stranded DNA binding MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005694 chromosome CC
GO:0005712 chiasma CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006298 mismatch repair BP
GO:0006310 DNA recombination BP
GO:0006312 mitotic recombination BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0007275 multicellular organism development BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009555 pollen development BP
GO:0009791 post-embryonic development BP
GO:0009845 seed germination BP
GO:0009987 cellular process BP
GO:0010154 fruit development BP
GO:0016445 somatic diversification of immunoglobulins BP
GO:0016446 somatic hypermutation of immunoglobulin genes BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0022414 reproductive process BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032300 mismatch repair complex CC
GO:0032389 MutLalpha complex CC
GO:0032501 multicellular organismal process BP
GO:0032502 developmental process BP
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044427 obsolete chromosomal part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044454 obsolete nuclear chromosome part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0048229 gametophyte development BP
GO:0048316 seed development BP
GO:0048608 reproductive structure development BP
GO:0048731 system development BP
GO:0048856 anatomical structure development BP
GO:0050896 response to stimulus BP
GO:0051716 cellular response to stimulus BP
GO:0061458 reproductive system development BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090351 seedling development BP
GO:0097159 organic cyclic compound binding MF
GO:0099086 synaptonemal structure CC
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1990391 DNA repair complex CC
KEGG Term Name Description
map03430 Mismatch repair DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.